Publications by Hiyori Saito

Publications by authors named "Hiyori Saito"

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Effectors SifA, SpvB, SseF, SseJ, and SteA Contribute to Type III Secretion System 1-Independent Inflammation in a Streptomycin-Pretreated Mouse Model of Colitis.

Shigeki Matsuda Takeshi Haneda Hiyori Saito Tsuyoshi Miki Nobuhiko Okada

Infect Immun

September 2019

serovar Typhimurium ( Typhimurium) induces inflammatory changes in the ceca of streptomycin-pretreated mice. In this mouse model of colitis, the type III secretion system 1 (T3SS-1) has been shown to induce rapid inflammatory change in the cecum at early points, 10 to 24 h after infection. Five proteins, SipA, SopA, SopB, SopD, and SopE2, have been identified as effectors involved in eliciting intestinal inflammation within this time range.

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- Hiyori Saito's research focuses on the role of various effector proteins in inducing inflammation through the Type III Secretion System (T3SS) in a mouse model of colitis.
- In the study published in "Infect Immun," Saito identified that the proteins SifA, SpvB, SseF, SseJ, and SteA contribute to inflammation independently of T3SS-1, showcasing the complexity of immune responses in the gastrointestinal tract.
- The findings highlight the significant impact of serovar Typhimurium on inducing rapid inflammatory changes, which may enhance our understanding of bacterial pathogenesis and host responses in colitis.

Publications by authors named "Hiyori Saito"

Effectors SifA, SpvB, SseF, SseJ, and SteA Contribute to Type III Secretion System 1-Independent Inflammation in a Streptomycin-Pretreated Mouse Model of Colitis.

Synopsis of recent research by authors named "Hiyori Saito"