[The relationship between periodontal disease and osteoporosis in animals].

Osteoporosis is suspected as a potential risk factor in periodontal disease. However, the detailed relationship between these diseases is unclear. The particular models of laboratory animals for the both diseases are needed to clarify the interactive influence route.

Effects of scaling and root planing on the amounts of interleukin-1 and interleukin-1 receptor antagonist and the mRNA expression of interleukin-1beta in gingival crevicular fluid and gingival tissues.

Objective: The purpose of this study was to evaluate the relationship between the clinical changes after non-surgical periodontal therapy and interleukin 1 (IL-1) in gingival crevicular fluid (GCF) and gingival tissues from patients with chronic periodontitis.

Background: The inflammatory responses mediated by IL-1 play an important role in periodontal tissue destruction. Although numerous studies have attempted to elucidate the dynamic movement involved in chronic periodontitis, the results have often conflicted.

Effect of restraint stress on the progression of experimental periodontitis in rats.

Background: A hypothesis of an increased risk for destructive periodontal diseases due to psychological stress has long been promoted. However, the research on stress and periodontal disease is still in its infancy. One of the reasons is thought to be that there is no suitable animal model for investigating the relationship.