Publications by authors named "Hitomi Okita"
Objective: To evaluate the effect of intravenous administration of human multilineage-differentiating stress-enduring (Muse) cells on rat postoperative erectile dysfunction (ED) with cavernous nerve (CN) injury without an immunosuppressant.
Materials And Methods: Male Sprague-Dawley rats were randomised into three groups after CN crush injury. Either human-Muse cells, non-Muse mesenchymal stem cells (MSCs) (both 1.
Article Synopsis
- Human amniotic epithelial cells (hAECs) are promising for cell transplantation, but the effectiveness of intraportal infusion for their delivery in vivo remains untested.
- This study involved infusing hAECs into Wistar/ST rats via four different routes (intraportal, spleen, tail veins, penile veins) to observe cellular distribution using imaging techniques.
- Results highlighted that intraportal infusion showed the best liver targeting, while spleen infusion risked thrombosis and systemic administration led to severe complications such as pulmonary embolism.*