Publications by authors named "Hitomi Ohmaki"
Article Synopsis
- Japan is seeing an increase in endangered bird species, prompting the need for conservation efforts.
- Researchers have developed induced pluripotent stem cells (iPSCs) from three endangered birds using specific reprogramming factors, indicating potential for species recovery.
- The study shows that while iPSCs from these species have distinct characteristics, they could play a significant role in conserving genetic resources and aiding conservation efforts.
Although immortalized cultured cells are useful for various functional assays or transcriptome analysis, highly efficient and reproducible immortalization methods have not been developed in avian-derived cells. We introduced the simian virus 40 T antigen (SV40T) and human papillomavirus (HPV)-E6E7 to chick and Okinawa rail (endangered species)derived fibroblast. As a result, neither the SV40T nor E6E7 genes could induce avian cell immortality.
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