Association of haptoglobin phenotypes with markers of diabetic nephropathy in Type 2 diabetes mellitus.

Background: Recent studies have suggested an inheritable influence of haptoglobin phenotypes on the development of microalbuminuria in diabetic patients. In this study, we aimed to investigate whether microalbuminuria and serum levels of Cystatin C (Cys C) were correlated with haptoglobin phenotypes in patients with Type 2 diabetes mellitus.

Methods: Fasting blood samples and first morning urine specimens were collected from 216 patients with type 2 diabetes (mean age 60.