Publications by authors named "Hisayo Iwasaki"
Article Synopsis
- - The study focused on Japanese patients with acute myeloid leukemia (AML) specifically looking at those with unusual cup-like nuclei, finding that about 23% of AML cases studied had this unique feature.
- - All identified cases of cup-like AML were linked to FLT3-ITD mutations and showed a high occurrence of complications like disseminated intravascular coagulation and acute cerebral infarction.
- - The findings suggest that AML with cup-like nuclei may be more prevalent than previously thought, indicating the need for healthcare professionals to recognize and understand this specific morphology.
The 2017 World Health Organization (WHO) classification states that acute promyelocytic leukemia (APL) always presents with strong myeloperoxidase staining. However, we herein report of a 40-year-old woman with the microgranular variant of acute promyelocytic leukemia presenting with weak myeloperoxidase (MPO) staining. The leukemic cells were morphologically similar to monocytic cells, showing distorted-shaped nuclei and weak MPO staining.
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