Publications by authors named "Hisatoshi Bekki"
Background: Ezetimibe ameliorates serum low-density lipoprotein cholesterol (LDL-c) and it has been approved for the treatment of hypercholesterolemia. However, the effects of ezetimibe on specific biomarkers have not been fully clarified in obese Japanese patients.
Methods: A total of 101 patients (47 males and 54 females) were registered in this study during 2011 and 2012.
Background: There is a growing body of evidence that blood pressure (BP) level is one of the major determinants of cardiovascular morbidity and mortality in individuals, including elderly people. However, to achieve a target BP level in the elderly is more difficult compared with patients aged <65 years. Current guidelines recommend combination drug therapy with different modes of action for the treatment of elderly patients with moderate hypertension (HT).
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- Blood pressure control is crucial for reducing cardiovascular risks in patients with essential hypertension, but many struggle to meet targets with single-drug therapy.
- This study investigated whether switching from 80 mg valsartan or 8 mg candesartan to 40 mg telmisartan along with 5 mg amlodipine could enhance blood pressure control in patients who weren't meeting their goals.
- Results showed that the new combination significantly lowered both clinic systolic and diastolic blood pressure over 12 weeks, indicating that telmisartan may be more effective than valsartan or candesartan in combination with amlodipine for better blood pressure management.