Publications by authors named "Hisato Oku"

Article Synopsis
  • A study investigated the effects of low-dose combined oral contraceptives (COCs) on anticoagulation factors in 394 Japanese women who started using COCs.
  • Results showed significant decreases in free protein S (PS) antigen and activity levels and antithrombin activity, while protein C (PC) activity levels increased during both the active and placebo phases of the COC regimen.
  • The study found that certain COC formulations (30 µg ethinylestradiol/desogestrel or 20 µg ethinylestradiol/drospirenone) led to larger reductions in PS levels compared to others, and effects were also noted during the hormone-free intervals.
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•Endometrial stromal sarcoma disseminated after morcellation•Complete remission of pelvic recurrence was achieved by oophorectomy.•Laparoscopic confirmation of remission of recurrent disease.

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Study Objective: To estimate the efficacy of the vasopressin injection technique for laparoscopic cystectomy of ovarian endometriomas with regard to operative time and coagulation events.

Design: Prospective study (Canadian Task Force Classification II-1)

Setting: Osaka Central Hospital in Osaka, Japan

Patients: Fifteen women with single lobular similarly-sized ovarian endometrioma.

Interventions: Women who planned to undergo laparoscopic cystectomy of endometrioma were allocated randomly to 3 groups: (1) ordinary laparoscopic cystectomy without injection, (2) laparoscopic cystectomy with the injection of saline solution, and (3) laparoscopic cystectomy with the vasopressin injection technique.

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Context: The effect of constant rich iodine intake, especially during pregnancy, has not been well understood.

Objective: The objective was to examine urinary iodine excretion and thyroid function in early pregnancy in Japanese healthy women. We also studied fetal maturation and child development in these women.

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