Publications by authors named "Hisamoto Kowa"
Objective: We conducted a 3-year prospective study on olfaction of patients with Parkinson's disease (PD) in order to examine the severity and frequency of smell disorder in PD using odor identification test, Open Essence (OE) and to verify the validity of olfactory tests as a predictor of cognitive symptom onset of PD.
Patients And Methods: We conducted a prospective study by performing an annual examination over a 3-year period. For 56 cases diagnosed with PD by the Department of Neurology at our hospital, OE and Jet Stream Olfactometry (JSO) were performed to assess the olfactory function, and Mini-Mental-State Examination (MMSE) was conducted to measure cognitive impairment.
Characteristics of Smell Identification Test in Patients With Parkinson Disease.
Clin Exp Otorhinolaryngol
May 2019
Article Synopsis
- Parkinson's disease (PD) often causes olfactory (smell) disorders early on due to the buildup of Lewy bodies, which can help in the early diagnosis and treatment of the disease.* -
- A study involving 39 PD patients and 31 control patients with postviral olfactory disorder used different olfactory tests, showing significant differences in the subjective smell assessments (VAS scores) but no major differences in objective detection and recognition thresholds.* -
- The findings suggest that PD patients tend to incorrectly identify smells rather than recognizing them as "undetectable," indicating a specific pattern of olfactory dysfunction that may aid in differentiating PD from other olfactory disorders.*