Time-course microarrays reveal early activation of the immune transcriptome in a choline-deficient mouse model of liver injury.

Aims: Choline-deficient diet is extensively used as a model of nonalcoholic fatty liver disease (NAFLD). In this study, we explored genes in the liver for which the expression changed in response to the choline-deficient (CD) diet.

Main Methods: Male CD-1 mice were divided into two groups and fed a CD diet with or without 0.