Objective: To evaluate the influence of firing procedures on the marginal distortion of electroformed metal-ceramic crown restorations.
Method And Materials: Twenty-four standardized specimens were fabricated using a gold-electroforming system and were characterized by 3 finish line forms: shoulder (S-type), rounded shoulder (RS-type), and deep chamfer (DC-type) preparations. Marginal discrepancies were measured at 6 stages: before the firing procedures, after the gold-bonder application, after the opaque porcelain firing, after the dentin porcelain firing, after the enamel porcelain firing, and after the glazing firing.
Statement Of Problem: Gold electroformed metal-ceramic restorations have been promoted as alternatives to conventional metal-ceramic restorations. However, little is known about the relationship between tooth preparation design and marginal adaptation for this type of crown.
Purpose: This study evaluated the influence of 3 different finish line designs on the marginal adaptation of electroformed metal copings and metal-ceramic crowns.
Interleukin-1 (IL-1) plays key roles in altering cartilage matrix turnover. This turnover is regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs). In the present study, we examined the effect of IL-1beta on cell proliferation, alkaline phosphatase (ALPase) activity, and the expression of MMPs, and TIMPs in chondrocytes derived from normal human femoral cartilage.
View Article and Find Full Text PDFWe examined the effect of the inflammatory mediator interleukin-1alpha (IL-1alpha) on cell proliferation, alkaline phosphatase (ALPase) activity, and the expressions of cartilage matrix proteins, bone morphogenetic protein-2 (BMP-2), and BMP-2 receptors in human chondrosarcoma cell line OUMS-27 (chondrocytes). The cells were cultured with Dulbecco's modified Eagle's medium containing 15% fetal bovine serum with 0, 1, 10, or 100 units/ml of IL-1alpha for up to 14 days. The expressions of cartilage matrix proteins, BMP-2, and BMP-2 receptors were estimated by determining mRNA levels using semiquantitative or real-time PCR and/or by determining protein levels using Enzyme-linked immunosorbent assay.
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