Publications by authors named "Hirunika U Kumarasinghe"
Article Synopsis
- * The article discusses methods to analyze how these scaffolds interact with cells, focusing on how they degrade and how cell growth (biomass) can be measured through various metrics like cell weight and extracellular matrix (ECM) deposition.
- * It presents detailed protocols for creating silk fiber scaffolds, cultivating specific mouse cells (C2C12), and monitoring key parameters, contributing to the development of more efficient cellular agriculture techniques.
The study of human intestinal physiology and host-microbe interactions is crucial for understanding gastrointestinal health and disease. Traditional two-dimensional cell culture models lack the complexity of the native intestinal environment, limiting their utility in studying intestinal biology. Here, we present a detailed protocol for the set up and utilization of a three-dimensional (3D) in vitro bioreactor system for human intestinal studies and bacterial co-culture.
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