Publications by authors named "Hiroyuki Nakata"

Background: To evaluate antibody responses against the primary series of vaccination of severe acute respiratory syndrome coronavirus-2 [SARS-CoV-2] vaccines in the staff and residents of Japanese geriatric intermediate care facilities.

Methods: All subjects (159 staff and 96 residents) received two doses of the BNT162b2 mRNA vaccine 3 weeks apart. Baseline data of subject were collected using a structured form.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to understand the incidence and risk factors for norovirus-related diarrhea among elderly residents in Japanese geriatric intermediate care facilities.
  • Conducted from November 2018 to April 2020, the study followed 1,727 residents across 10 facilities, finding that 74 developed diarrhea, with 13 testing positive for norovirus—resulting in an incidence rate of 10.11 per 1000 person-years.
  • Key risk factors for developing norovirus-related diarrhea included a higher care-needs level, hypertension, stroke, and using a cane, indicating a correlation between health conditions and susceptibility to this infection in elderly populations.
View Article and Find Full Text PDF

Ultraviolet photochemistry of iron pentacarbonyl, Fe(CO), was investigated with resonantly enhanced multiphoton ionization (REMPI) spectroscopy and ion imaging. The REMPI spectrum of CO photofragments, generated by ultraviolet irradiation of Fe(CO), showed the generation in the highly vibrationally excited states with = 11-15. Analysis of the band intensities observed in the 213-235 nm region indicated that the high- CO generation was maximized at around 220 nm.

View Article and Find Full Text PDF

Traditional Japanese Bizen stoneware is produced by firing a specific type of green clay in a wood-fired kiln at approximately 1200 °C. During this process, single crystalline branched dendrite-like particles of Al-substituted ε-FeO (ε-FeAlO) with widths and lengths of approximately 15 and 30 μm, respectively, are formed on the surface of the ceramic. Composite particles consisting of ε-FeO epitaxially connected to spinel structure compounds [comprising the Fe-substituted spinel (Mg,Fe)(Al,Fe)O and γ-FeO)] with lengths of approximately 3 μm are also generated.

View Article and Find Full Text PDF

The photodissociation dynamics of the heteroleptic Co(CO)NO complex were investigated in the metal-to-carbonyl (CO) ligand charge-transfer band to compare the reactivity of the CO and nitrosyl (NO) ligands. The final state distributions of both the CO and NO fragments were measured using resonance-enhanced multiphoton ionization (REMPI) spectroscopy and velocity-map ion-imaging. The primary CO photofragment was differentiated from the secondary fragments of the subsequent unimolecular decomposition of coordinatively unsaturated intermediates by comparing the momentum distributions.

View Article and Find Full Text PDF

Aim: The aim of this study was to identify factors affecting the final diagnosis of cough.

Materials And Methods: This study recruited 463 consecutive patients who visited five Japanese general hospitals due to cough from October 2006 to September 2007. Of these, 418 patients (90%) who completed a questionnaire designed to acquire data regarding clinical manifestations of cough were included.

View Article and Find Full Text PDF

Malignant mesothelioma is relatively rare and usually presents with pleural thickening and effusion at onset. In this report, we describe a 67-year-old male patient whose initial manifestation of mesothelioma was a large mass in the left flank. Mesothelioma was diagnosed from needle biopsy specimens, and, after radiotherapy, the tumor did not recur in this area.

View Article and Find Full Text PDF

Background: Cough variant asthma has recently been described, mainly as airway inflammation in relation to bronchial asthma, but the relationship between the two types of asthma remains unclear. Further studies of cough receptor sensitivity are necessary to fully characterize cough variant asthma.

Methods: We assessed the relevance of testing cough sensitivity using an Astograph with continuous capsaicin inhalation, and compared the results with those obtained using intermittent inhalation.

View Article and Find Full Text PDF

o-Nitrobenzyl photochemistry as induced by UV-A irradiation was applied to a photoactivated drug releasing system based on a molecular beacon strategy. A stem-and-loop structured oligodeoxynucleotide (ODN) possessing a photoreactive o-nitrobenzyl chromophore at the 3'-end and 1-aminonaphthalene quencher at the 5'-end underwent conformational change into a conventional double strand structure by hybridization with a specified target DNA. The intrinsic stem-and-loop structure suppressed photoactivated release of benzoic acid as a phantom drug from the o-nitrobenzyl chromophore because of intramolecular quenching by the 1-aminonaphthalene unit in close proximity to the chromophore.

View Article and Find Full Text PDF

Background: Some patients develop asthmatic symptoms such as wheezing and dyspnea during the course of cough variant asthma (CVA), which are considered precursors of classical asthma.

Objectives: To identify the characteristics of such patients, we investigated the nature of CVA patients with or without developing bronchial asthma in the longitudinal study.

Methods: In 28 CVA patients whom we could observe over 5 years, duration of coughing, physical examination findings, pulmonary function and bronchial hyperresponsiveness to inhaled methacholine were retrospectively assessed.

View Article and Find Full Text PDF

We report a case of postpartum cerebral angiopathy with headache; a rare entity that affects women within the early postpartum period. Cerebral angiography revealed multiple segmental narrowings of major cerebral arteries. The patient was monitored with transcranial color-coded sonography of the middle cerebral artery.

View Article and Find Full Text PDF