Publications by authors named "Hiroyuki Miyazawa"
Wenckebach-periodic VA prolongation and abrupt shortening of HH interval during tachycardia indicate (i) a retrograde block at the upper common pathway that manifested a retrograde atrial activation via the superior slow pathway, and (ii) an antegrade return of a retrograde atrial activation to His bundle via the fast pathway.
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- The study evaluates the FIB4 index, a noninvasive marker, to see if it can predict adverse outcomes, particularly all-cause mortality, in patients with ST-elevation myocardial infarction (STEMI) who received primary coronary intervention.
- Researchers analyzed 1,354 STEMI patients, categorizing them based on their FIB4 index values into low, intermediate, and high risk for mortality during a follow-up period of 4.3 years.
- Findings indicate that higher FIB4 index values significantly correlate with increased all-cause mortality, establishing it as an independent risk predictor in this patient population.
Article Synopsis
- - Anamorelin is a medication that activates ghrelin receptors and is used to treat muscle wasting in cancer patients, but it has the potential to cause serious heart rhythm issues.
- - A case study revealed a patient experiencing dangerously wide QRS tachycardia, making it difficult to identify the exact cause of the heart problem.
- - Stopping anamorelin treatment returned heart rhythms to normal, emphasizing the need for regular ECG monitoring and extra support for patients with liver issues who may experience drug toxicity.
Article Synopsis
- A study investigated the link between high uric acid levels (hyperuricemia) and the recurrence of arrhythmia after catheter ablation for paroxysmal atrial fibrillation (AF), finding that hyperuricemia may increase the risk of AF returning.
- The research divided patients into two groups based on their uric acid levels and discovered that those with hyperuricemia had a higher alcohol consumption rate and a lower rate of remaining free from AF after treatment.
- Key factors predicting AF recurrence included hyperuricemia, alcohol consumption of 20g/day or more, female gender, and higher brain natriuretic peptide levels, suggesting that both hyperuricemia and alcohol intake independently influence AF recurrence risks
Article Synopsis
- The study investigates the relationship between the fibrosis-4 (FIB-4) index and the recurrence of atrial fibrillation (AF) after catheter ablation in patients with and without heart failure (HF).
- 1,184 patients who underwent AF catheter ablation were categorized into low, intermediate, and high-risk groups based on their FIB-4 scores, with further classification between those with HF and those without.
- Results showed no significant recurrence differences in the non-HF group, but higher recurrence rates were observed in the intermediate and high-risk HF groups compared to the low-risk HF group, suggesting the FIB-4 index could predict AF recurrence in HF patients, especially those without paroxysmal AF.
Article Synopsis
- Functional mitral regurgitation (FMR) is common in patients with atrial fibrillation (AF) and can worsen heart failure (HF), prompting a study of its effects on catheter ablation outcomes in HF patients.
- In a study of 280 patients with HF and nonparoxysmal AF, FMR cases decreased significantly from 54.6% at baseline to 25% after one year following ablation, with many experiencing a reduction in severity.
- Most patients (97.9%) maintained sinus rhythm after a year, and those with improved FMR showed better cardiac parameters compared to those without improvement, indicating a positive feedback loop for heart function after ablation.
Introduction: Herein, we present a rare case of the successful ablation of an accessory pathway (AP) involving the Marshall Bundle (MB) and coronary sinus musculature (CSM) in a 40-year-old man with Wolff-Parkinson-White syndrome.
Methods And Results: An orthodromic reciprocating tachycardia (ORT) was inducible with the earliest atrial activation site located at the posterolateral mitral annulus. The local conduction and the cycle length of ORT was prolonged by peri-mitral ablation; however, it failed to block the AP.
Article Synopsis
- The study investigated the effects of excimer laser coronary angioplasty (ELCA) versus manual aspiration thrombectomy on patients with acute myocardial infarction (MI), specifically ST-segment elevation MI (STEMI).
- A total of 143 patients were analyzed, showing a significant difference in peak CK-MB levels, with lower levels in the ELCA group compared to the aspiration group.
- While both methods showed similar results for myocardial salvage, ELCA led to better improvements in left ventricular systolic function, evidenced by higher ejection fraction and peak emptying rate.
Article Synopsis
- The study examined how coexisting sick sinus syndrome (SSS) affects the success of catheter ablation (CA) in treating atrial fibrillation (AF) through a large-scale registry involving over 5,000 patients.
- Findings showed no significant differences in AF-free survival rates between patients with SSS and those without, indicating that SSS does not negatively impact the effectiveness of CA.
- Although 48 patients with SSS needed pacemakers, which correlated with AF recurrence, the majority (85.3%) did not require one within three years post-ablation, suggesting that most patients with SSS can have successful outcomes.
Article Synopsis
- The study investigates the relationship between atrial defibrillation threshold (ADFT) and the recurrence of atrial tachyarrhythmia in patients undergoing catheter ablation for non-paroxysmal atrial fibrillation (AF).
- A total of 368 patients were categorized into low ADFT (<20 J) and high ADFT (≥20 J) groups, revealing that the high ADFT group had a significantly higher rate of AF recurrence (30.6% vs. 16.7%) over a 2.6-year follow-up period.
- The findings suggest that a high ADFT is a notable risk factor for AF recurrence specifically in patients with long-standing persistent AF, while it does not
Cryoablation for atrioventricular nodal re-entrant tachycardia associated with persistent left superior vena cava.
Indian Pacing Electrophysiol J
August 2021
Catheter ablation for atrioventricular nodal re-entrant tachycardia (AVNRT) in patients with persistent left superior vena cava (PLSVC) is challenging because of anatomical abnormalities of Koch's triangle associated with the enlarged coronary sinus ostium. We present the Case of successful ablation in a patient with PLSVC using the cryoablation technique. The ablation was successfully performed without damaging the conduction system by virtue of "cryomapping" and "cryoadhesion.
View Article and Find Full Text PDFBackground: The relationship between nutritional status and the incidence or prognosis of atrial fibrillation (AF) has been reported, but no studies have described the relationship between the outcomes of AF catheter ablation (CA) and nutritional status as assessed by various scoring tools. We aimed to verify the hypothesis that preoperative nutritional status is associated with arrhythmia recurrence after CA for AF.
Methods and results: We evaluated 913 patients (age, 67±10 years; men, 72%; paroxysmal AF, 56%) who underwent CA for AF between November 2011 and November 2017.
Aims: We aimed to examine the benefits of catheter ablation in patients with non-paroxysmal atrial fibrillation (AF) accompanied by heart failure (HF) with preserved ejection fraction (HFpEF), in comparison with the benefits in patients with AF accompanied by HF with reduced ejection fraction (HFrEF) or patients with no HF.
Methods And Results: From 1173 consecutive patients undergoing catheter ablation, 502 with non-paroxysmal AF were divided into three groups: no history of HF [plasma B-type natriuretic peptide (BNP) <100 pg/mL and no HF hospitalization; n = 125], HFpEF [left ventricular (LV) EF ≥50%; n = 293], and HF with midrange EF (HFmrEF) + HFrEF (LVEF <50%; n = 84) groups. The endpoints were AF recurrence at 1 year, changes in symptomatic and image-based functional status, and changes in BNP levels from baseline to 1 year.