Publications by authors named "Hiroyuki Matsuta"
Article Synopsis
- Bright light exposure (BL) was shown to increase the volume of the left hippocampal dentate gyrus (DG) in patients with mood disorders, based on a 4-week randomized controlled trial.
- Patients with mood disorders were divided into two groups: one receiving BL (10,000 lx) and the other dim light (50 lx), with assessments and MRIs conducted before and after the intervention.
- Results indicated that the BL group had increased volumes in both the left DG-head and left DG-total, along with a positive correlation between DG volume increase and improvement in mood scores.
The neural mechanisms underlying gross and fine motor dysfunction after subarachnoid hemorrhage (SAH) remain unknown. The γ-aminobutyric acid (GABA) deficit hypothesis proposes that reduced neuronal GABA concentrations and the subsequent lack of GABA-mediated inhibition cause motor impairment after SAH. This study aimed to explore the correlation between GABA levels and a behavioral measure of motor performance in patients with SAH.
View Article and Find Full Text PDFA man in the 70s fell on a bamboo and punctured his left upper eyelid. CT of the head showed fractures of the medial and superior walls of the left orbit, intracranial traumatic subarachnoid haemorrhage, intraventricular haematoma and left frontal cerebral contusion. He was treated conservatively.
View Article and Find Full Text PDFContinuous theta-burst stimulation (cTBS) is a noninvasive repetitive brain stimulation protocol that suppresses the excitability of the primary motor cortex. It induces cerebral cortical inhibition by increasing inhibitory interneuronal excitability that is associated with increases in gamma-aminobutyric acid (GABA) concentration in the stimulated cortices. cTBS has been applied in the rehabilitation of stroke patients to modulate interhemispheric imbalance.
View Article and Find Full Text PDFArticle Synopsis
- Bright light therapy (BLT) is investigated for its effects on neurogenesis in the human dentate gyrus (DG), a region linked to mood disorders, following previous findings in rats.
- A 4-week randomized trial with healthy participants compared effects of bright light exposure (10,000 lux) versus dim light (50 lux) on DG volume, using MR imaging.
- Results showed significant growth in the left DG-head volume for the bright light group, indicating that BLT may induce neurogenesis in humans, highlighting a new mechanism of its therapeutic action.
Background: Pulsed arterial spin-labeling, diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (MRS) are useful for predicting glioma survival. We performed a comparative review of multiple parameters obtained using these pulse sequences on 3-Tesla magnetic resonance imaging (MRI) including the molecular status and Ki-67 labeling index in newly diagnosed supratentorial glioblastomas.
Methods: A total of 35 patients with glioblastomas underwent pulsed arterial spin-labeling, DTI, and MRS studies using 3-Tesla MRI preoperatively.