Synopsis of recent research by authors named "Hiroyuki Hosokawa"
- Hiroyuki Hosokawa's research focuses on the interplay between immune responses and cancer development, particularly through the regulation of transcription factors and innate immune cells, such as the role of plasminogen activator inhibitor-1 in immune evasion by tumors.
- His studies highlight critical cellular mechanisms underlying T-cell development and lineage commitment, emphasizing the contributions of transcription factors like Runx and Bcl11b in determining T-cell fate from progenitor cells.
- Hosokawa's work also extends to metabolic regulation by immune cells, showcasing how liver group 2 innate lymphoid cells influence blood glucose levels, illustrating the complex relationship between immunity and metabolism in health and disease.
