Urodynamic and gait analyses in multiple system atrophy.

Background: Limited attention has been paid to the relationship between bladder dysfunction and motor disorder in multiple system atrophy (MSA).

Objective: We aimed to correlate pressure-flow urodynamic parameters with video-gait analysis parameters in MSA.

Methods: We recruited 34 patients with MSA: 20 men, 14 women; age 64.

Imidafenacin on bladder and cognitive function in neurologic OAB patients.

Objective: To explore imidafenacin's effects on bladder and cognitive function in neurologic overactive bladder (OAB) patients.

Methods: Sixty-two subjects (25 men, 37 women; mean age 70 years (25-86) with OAB due to neurologic diseases) were enrolled in the study. We conducted a urinary symptom survey and cognitive tests (MMSE, FAB, ADAS-cog) in all patients.

Inhibitory control task is decreased in vascular incontinence patients.

Objective: 'Vascular incontinence' is a part of elderly incontinence due to cerebral white matter change (WMC). We studied the relationship between performance on several cognitive tasks and urodynamic detrusor overactivity (DO) in patients with vascular incontinence.

Methods: We recruited 40 patients with lower urinary tract symptoms due to WMC [20 male, 20 female; mean age 77 years (60-89 years)].

Weak detrusor contractility correlates with motor disorders in Parkinson's disease.

Limited attention has been paid to the relationship between urinary symptoms or urodynamic findings and motor disorders in Parkinson's disease (PD). We aimed to correlate pressure-flow urodynamic parameters with video-gait analysis parameters in PD. We recruited 41 patients with PD (25 men and 16 women; age, 70.

Engineering the substrate specificity of Alcaligenes D-aminoacylase useful for the production of D-amino acids by optical resolution.

D-Aminoacylase from Alcaligenes xylosoxydans subsp. xylosoxydans A-6 (AxD-NAase) offers a novel biotechnological application, the production of D-amino acid from the racemic mixture of N-acyl-DL-amino acids. However, its substrate specificity is biased toward certain N-acyl-D-amino acids.