Inhibition of experimental choroidal neovascularization by an anti-growth agent inhibiting vascular endothelial development.

Purpose: To determine whether FR118487, a recently developed angiogenesis inhibitor, affects experimental choroidal neovascularization (CNV) induced by laser photocoagulation in pigmented rats.

Methods: Focal laser photocoagulation (argon green 50 mW, 0.04 seconds, 200 microm) was applied to the retinochoroid of normal Brown Norway rats.

Hyperbaric oxygen therapy reduces visual field defect after macular hole surgery.

Background And Objective: One of the serious complications that may arise after macular hole (MH) surgery is a temporal visual fields (TVF) defect. We hypothesized that hyperbaric oxygen (HBO) therapy improves the visual field (VF) in these patients.

Materials And Methods: Vitrectomy for MH was performed on 73 eyes from 1994 to 1997.