Dosimetric impact of stopping power for human bone porosity with dual-energy computed tomography in scanned carbon-ion therapy treatment planning.

Few reports have documented how the accuracy of stopping power ratio (SPR) prediction for porous bone tissue affects the dose distribution of scanned carbon-ion beam therapy. The estimated SPR based on single-energy computed tomography (SECT) and dual-energy CT (DECT) were compared for the femur of a Rando phantom which simulates the porosity of human bone, NEOBONE which is the hydroxyapatite synthetic bone substitute, and soft tissue samples. Dose differences between SECT and DECT were evaluated for a scanned carbon-ion therapy treatment plan for the Rando phantom.

Commissioning a newly developed treatment planning system, VQA Plan, for fast-raster scanning of carbon-ion beams.

In this study, we report our experience in commissioning a commercial treatment planning system (TPS) for fast-raster scanning of carbon-ion beams. This TPS uses an analytical dose calculation algorithm, a pencil-beam model with a triple Gaussian form for the lateral-dose distribution, and a beam splitting algorithm to consider lateral heterogeneity in a medium. We adopted the mixed beam model as the relative biological effectiveness (RBE) model for calculating the RBE values of the scanned carbon-ion beam.

[Noninvasive assessment of coronary artery with substantial contrast volume reduction using 320-detector row computed tomography: a feasibility study].

The recently introduced 320-detector row computed tomography (320-row CT) allows very fast volumetric acquisition of the entire heart. Because the total amount of contrast agent required for CT coronary angiography (CTCA) depends directly on the acquisition time, 320-row CTCA would substantially reduce the contrast agent dose. The objective of this retrospective study was to evaluate the feasibility of contrast volume reduction on 320-row CTCA compared with 64-detector row CTCA (64-row CTCA).