Publications by authors named "Hiroya Namba"
Article Synopsis
- The study aimed to develop an automatic method for evaluating bone marrow (BM) cellularity using image analysis, moving away from the reliance on visual estimates.
- Researchers analyzed hematoxylin and eosin (HE)-stained bone marrow specimens from patients, comparing three image analysis methods against traditional visual assessments from pathology reports.
- Method C proved to be the most effective, achieving a high correlation with visual estimates and accurately detecting both non-fatty and cell nuclear areas in the bone marrow samples.
Background: Pregnancy is a risk factor for venous thromboembolism (VTE) due to increased coagulation factor activity and decreased protein S activity. However, thrombosis markers for predicting VTE in pregnancy remain controversial. This study aimed to investigate the relationship between VTE risk and thrombosis markers in pregnant women and to identify markers related to VTE risk.
View Article and Find Full Text PDFBackground: Emicizumab, a bispecific monoclonal antibody for hemophilia A (HA), has strong pharmacodynamic effects in several coagulation assays resulting in dosing difficulties with Factor VIII (FVIII) concentrates during bleeding emergencies.
Materials And Methods: Single and multiple regression models were studied to estimate FVIII activity using 27 archived plasma samples from three patients with HA without inhibitor under emicizumab treatment. Explanatory variables were FVIII chromogenic assay (CSA), Ad|min1|, Ad|min2|, the number of seconds of APTT, and the FVIII one-stage assay (OSA), which were measured without idiotype antibodies.