Microstructural Characterization of Foam Formed by a Hydroxy Group-Containing Amino Acid Surfactant Using Small-Angle Neutron Scattering.

Small-angle neutron scattering, which has not been extensively utilized for foam characterization, can provide important insights into the microstructure of surfactant-stabilized foam. Small-angle neutron scattering in combination with several other techniques was herein employed to determine the microstructure of foams stabilized by hydroxy group-containing (C-EtOH-βAla) and hydroxy group-free (C-Me-βAla) surfactants of the amino acid type. Hydroxy group introduction at the amide nitrogen had no effect on the foam film thickness (∼26 nm in both cases) but increased the foam stability and suppressed draining, as hydrogen bonding between hydroxy groups and carboxylate ions increased the foam film strength.

Analysis of the enhanced stability of r(+)-alpha lipoic Acid by the complex formation with cyclodextrins.

R(+)-alpha lipoic acid (RALA) is one of the cofactors for mitochondrial enzymes and, therefore, plays a central role in energy metabolism. RALA is unstable when exposed to low pH or heat, and therefore, it is difficult to use enantiopure RALA as a pharma- and nutra-ceutical. In this study, we have aimed to stabilize RALA through complex formation with cyclodextrins (CDs).