[Analysis of usefulness of a whole blood interferon gamma assay (QuantiFERON TB-2G) for diagnosing active tuberculosis in immunocompromised patients].

Purpose: Recently, there have been many reports that QuantiFERON TB-2G (QFT-2G) is useful for diagnosing active tuberculosis. However, it remains controversial whether QFT-2G is useful for diagnosing active tuberculosis in immunocompromised patients as well as immunocompetent ones. Therefore, we analyzed whether QFT-2G sensitivity is decreased in immunocompromised patients compared with that in immunocompetent patients and what factors affect the QFT-2G sensitivity.