Downregulation of ARID1A, a component of the SWI/SNF chromatin remodeling complex, in breast cancer.

Recent studies unraveled that AT-rich interactive domain-containing protein 1A (ARID1A), a subunit of the mammary SWI/SNF chromatin remodeling complex, acts as a tumor suppressor in various cancers. In this study, we first evaluated ARID1A expression by immunohistochemistry in invasive breast cancer tissue specimens and assessed the correlation with the prognosis of patients with breast cancer. Non-tumorous mammary duct epithelial cells exhibited strong nuclear ARID1A staining, whereas different degrees of loss in ARID1A immunoreactivity were observed in many invasive breast cancer cells.

Impact of Lanthanoid Substitution on the Structural and Physical Properties of an Infinite-Layer Iron Oxide.

The effect of lanthanoid (Ln = Nd, Sm, Ho) substitution on the structural and physical properties of the infinite-layer iron oxide SrFeO was investigated by X-ray diffraction (XRD) at ambient and high pressure, neutron diffraction, and Fe Mössbauer spectroscopy. Ln for Sr substituted samples up to ∼30% were synthesized by topochemical reduction using CaH. While the introduction of the smaller Ln ion reduces the a axis as expected, we found an unusual expansion of the c axis as well as the volume.

Effect of X-ray exposure on the pharmaceutical quality of drug tablets using X-ray inspection equipment.

Context: X-ray inspection equipment is widely used to detect missing materials and defective goods in opaque containers. Its application has been expanded to the pharmaceutical industry to detect the presence of drug tablets in aluminum foil press-through packaging. However, the effect of X-rays on the pharmaceutical quality of drug tablets is not well known.

Synthesis and charge-carrier transport properties of poly(phosphole P-alkanesulfonylimide)s.

A new class of polyphospholes bearing alkanesulfonylimino moieties on the phosphorus(V) centers was prepared by the Pd-CuI-promoted Stille coupling reaction to investigate the charge-carrier transport properties of the π-networks of polyphospholes. Time-of-flight measurements have revealed that the poly(phosphole P-imide)s possess ambipolar charge-carrier mobilities of up to μ(electron) = 6 × 10(-3) cm(2) V(-1) s(-1) and μ(hole) = 4 × 10(-3) cm(2) V(-1) s(-1).

Oxyhydrides of (Ca,Sr,Ba)TiO3 perovskite solid solutions.

The oxyhydride solid solutions (Ca,Sr)TiO(3-x)H(x) and (Sr,Ba)TiO(3-x)H(x) have been prepared by reducing the corresponding ATiO(3) oxides with calcium hydride. Under the reaction conditions examined, a hydride content of x = 0.1-0.