Publications by authors named "Hiroshi Iwashita"
A 71-year-old man visited our hospital with dyspnea and left pleural effusion. Left pleural effusion was diagnosed as chylothorax by thoracentesis. He had no history of trauma or surgery, and there were no findings of malignant lymphoma or thrombosis.
View Article and Find Full Text PDFFor immune checkpoint inhibitor(ICI)-pretreated patients, docetaxel and ramucirumab(DTX plus RAM)combination therapy can be more effective than no treatment. Herein, we present the case of a patient who had been treated with ICIs and was thereafter successfully treated with DTX plus RAM. A 62-year-old man with primary pulmonary squamous cell carcinoma( PDL-1 tumor proportion score<1%)at clinical stage ⅠA2(cT1bN0M0)was treated as follows: 1)right upper lobectomy ND2a-2(pT1bN0M0, stage ⅠA2); 2)surgery for a solitary pleural metastasis 20 months later; 3)cisplatin plus vinorelbine for multiple pleural metastases as a first-line treatment 24 months after the initial surgery; and 4)nivolumab as a second-line treatment.
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- A new software has been created to correct the dynamic errors in impact force measurements from force transducers by analyzing their own output signals.
- The software estimates the uncertainty of the measurements and displays the results, allowing for more accurate data gathering.
- The experimental method, Levitation Mass Method, helps in determining correction parameters, and if manufacturers provide these parameters, users will benefit from improved accuracy in their measurements.
In 1971, the author reported an autopsy case of a 48-year-old Japanese man with polyneuropathy, skin hyperpigmentation, diabetes mellitus, and monoclonal gammopathy. Previously, a total of 2 cases of solitary myeloma accompanied by polyneuropathy and endocrinological disorders have been reported by Fukase et al in 1968 and by Shimomori and Kusumoto in 1970 in Japan. The author's case is the first reported non-myeloma case where polyneuropathy associated with dermatoendocrionological changes and dysglobulinemia was observed.
View Article and Find Full Text PDFOne thousand and thirty-one longstanding patients with subacute myelo-optico-neuropathy (SMON; 275 males, 756 females; mean age +/- S.D., 72.
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- A study conducted on SMON patients found a significant number with severe visual impairments and loss of mobility, indicating long-term effects of clioquinol intoxication.
- Among the analyzed patients, 81 experienced severe visual issues, with 22 being completely blind, which impacted their overall quality of life and independence.
- The findings suggest a crucial need for comprehensive support and resources for these severely affected patients to address their ongoing medical and social care requirements.