The prostatic and epididymal portions of rabbit vas deferens were different in the reactivity to electrical field stimulation (EFS), adenosine triphosphate (ATP) and noradrenaline (NA). The EFS produced biphasic contractile response; VIZ. the first rapid twitch like (phasic) and the second slow sustained (tonic) contraction.
View Article and Find Full Text PDFElectrical field stimulation (EFS) produced a biphasic contractile response; viz. initial rapid phasic contraction and second slow tonic contraction, in isolated guinea pig vas deferens. Pretreatment with the substrate of nitric oxide (NO) synthase (NOS), 1 mM L-arginine (L-ARG), augmented both the initial rapid and the second slow contractile responses to EFS (5 Hz, 0.
View Article and Find Full Text PDFContractile responses of rabbit and guinea pig vasa deferentia to electrical field stimulation (EFS) are compared. A muscarinic receptor blocking agent, 1 microM atropine markedly reduced phasic and tonic contraction induced by EFS (20 Hz, 0.5 msec, 30 V, for 30 sec) in rabbit vas deferens, while it only slightly depressed those in guinea pig vas deferens.
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