Clinical Features of Crowded Orbital Syndrome on Magnetic Resonance Imaging.

We have previously reported strabismus due to mismatch of orbital volume and globe as 'crowded orbital syndrome' (COS). In this study we have used magnetic resonance imaging (MRI) to investigate its clinical features. This has revealed that a globe with a similar axis occupies a larger volume in the orbit in patients with COS than in controls without strabismus.

Switching from concomitant therapy to tafluprost/timolol fixed combination.

Purpose: To evaluate the efficacy and safety of tafluprost/timolol fixed combination (TTFC).

Study Design: A prospective clinical study.

Methods: Twenty-eight patients (28 eyes) with primary open-angle glaucoma, who had used tafluprost and timolol gel for at least 3 months with good adherence, were enrolled.

Efficacy and safety of a switch to latanoprost 0.005% + timolol maleate 0.5% fixed combination eyedrops from latanoprost 0.005% monotherapy.

Background: The purpose of this prospective study was to investigate the intraocular pressure (IOP)-lowering effect and safety of latanoprost 0.005% + timolol maleate 0.5% fixed combination eyedrops, now available in Japan.

Divergence insufficiency associated with high myopia.

Purpose: Divergence insufficiency is generally regarded as a neurological event. While high myopia is not a well-known cause of divergence insufficiency, we frequently encounter divergence insufficiency in high-myopia patients. Thus, the purpose of this study was to report detailed information on such cases and examine mechanisms that might potentially be responsible for this disorder.