Impact of nurses' roles and burden on burnout during the COVID-19 pandemic: Multicentre cross-sectional survey.

Aim: To identify groups of nurses engaging in coronavirus disease (COVID-19) care who are most in need of organizational support.

Background: Overwhelming stress and susceptibility to burnout have been reported in nurses during the COVID-19 pandemic.

Methods: Nurses working at five hospitals that accepted COVID-19 patients answered the questionnaire.

[Evaluation of Body Temperature during Pancreaticoduodenectomy for Pancreatic Cancer in Elderly Patients Aged over 75 Years Old].

Background: Body temperatures in elderly patients undergoing a pancreaticoduodenectomy(PD)for treatment of pancreatic cancer have not been fully evaluated. We aimed to compare body temperature during a PD between elderly(75 years old)and non-elderly patients.

Methods: This retrospective study included patients who underwent PD between April 2012 and April 2014 at the Kanasgawa Cancer Center.

Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.

Gain-of-function mutations in the fibroblast growth factor receptor 3 gene (FGFR3) result in skeletal dysplasias, such as thanatophoric dysplasia and achondroplasia (ACH). The lack of disease models using human cells has hampered the identification of a clinically effective treatment for these diseases. Here we show that statin treatment can rescue patient-specific induced pluripotent stem cell (iPSC) models and a mouse model of FGFR3 skeletal dysplasia.