Publications by authors named "Hiromi Kawano"

Purpose: Adherence to medication is the most important challenge facing patients receiving oral anticancer treatment. This study aimed to evaluate the effects of a patient-centred medication self-management support programme in patients with metastatic breast cancer undergoing oral anticancer treatment.

Methods: This trial was a two-phased mixed-method randomised controlled study.

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  • * A surveillance study conducted in Japan collected urethral discharge samples from patients in 2009 and 2012 to test for antibiotic resistance in C. trachomatis isolates.
  • * Results showed that no resistant strains were found against common antibiotics like fluoroquinolones, tetracyclines, or macrolides during both years of the study.
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Neisseria gonorrhoeae is one of the most important pathogens causing sexually transmitted infection, and strains that are resistant to several antimicrobials are increasing. To investigate the trends of antimicrobial susceptibility among N. gonorrhoeae strains isolated from male patients with urethritis, a Japanese surveillance committee conducted the first nationwide surveillance.

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  • A nationwide surveillance study conducted in Japan from April 2009 to November 2010 examined antimicrobial susceptibility patterns of uropathogens causing acute uncomplicated cystitis in women, involving 43 hospitals.
  • The study identified E. coli as the most common bacteria (77.8%) in urine samples, with significant occurrences of S. saprophyticus in premenopausal women, while also analyzing their resistance to 19 antimicrobial agents.
  • Results indicated high susceptibility of E. coli to fluoroquinolones and cephalosporins, but a rising trend in fluoroquinolone-resistant and ESBL-producing strains highlights the need for careful selection of empirical treatments based on patient characteristics.
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Background: Dehydroepiandrosterone sulfate (DHEAS) is thought to be associated with life expectancy and anti-aging. However, its biological significance in atherosclerosis remains controversial. Therefore, the aim of this study was to determine whether DHEAS is associated with development of carotid atherosclerosis in subjects with cardiovascular risk factors.

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