Publications by authors named "Hiromi Hirasawa"

Article Synopsis
  • Dialysis patients face a heightened risk of developing renal cell carcinoma (RCC), but distinguishing RCC from benign cysts can be challenging with standard imaging techniques like CT and ultrasound.
  • This study conducted between 2012 and 2016 used FDG-PET/CT to screen for RCC in 150 participants with end-stage renal disease, with evaluations made by three radiologists.
  • The results showed that FDG-PET/CT had a high sensitivity (100%) and negative predictive value (100%), ultimately diagnosing RCC in seven out of twenty patients identified as positive for malignancy.
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Purpose: To identify gadolinium-based contrast agents (GBCAs)-related and patient-related risk factors for acute adverse reactions (AARs), and to examine the incidence and severity of repeated AARs.

Methods: This study retrospectively evaluated all intravenous GBCA injections in MRI studies at a single institution from January 2012 to September 2019. First-time AARs in patients without a past history of AARs and risk factors were assessed using multivariable regression models with generalized estimating equations.

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Purpose: To evaluate the clinical features and risk factors of iodinated contrast media (ICM)-induced anaphylaxis.

Methods: This retrospective study included all patients undergoing contrast-enhanced computed tomography (CT) with intravenous ICM administration (iopamidol, iohexol, iomeprol, iopromide, ioversol) at our hospital between April 2016 and September 2021. Medical records of patients who experienced anaphylaxis were reviewed, and the multivariable regression model using generalized estimating equations was employed to eliminate the effect of intrapatient correlation.

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Purpose: To analyze the appropriateness of primary response for anaphylaxis due to iodinated contrast media (ICM) or gadolinium-based contrast agents (GBCA).

Materials And Methods: This retrospective study included all patients in whom intravenous contrast agents (five types of ICMs and four types of GBCAs) were administered at our hospital between April 2016 and September 2021. For the patients who developed anaphylaxis, we obtained data on the time records of contrast injection, anaphylaxis onset, and intramuscular adrenaline (epinephrine) administration.

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Introduction: This study aimed to assess the utility of quantitative high-resolution computed tomography (HRCT) for determining the clinical course of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis-associated interstitial lung disease (MDA5 ILD).

Method: This study retrospectively analyzed the data of 34 patients with MDA5 ILD to determine the association between the clinical findings and extent of ILD via quantitative CT analysis at baseline and short-term follow-up. Quantified HRCT scores were evaluated as the lung severity score (LSS), percentage of opacity, and percentage of high opacity.

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Article Synopsis
  • The study aimed to assess the threshold dose of carbon-ion radiation therapy (C-ion RT) and its influencing factors in liver cancer patients by observing changes in MRI signal intensity post-treatment.
  • It involved a retrospective review of 60 patients and measured focal liver reaction (FLR) volume after treatment, while accounting for tumor volume changes and other relevant health metrics such as Child-Pugh score.
  • Results indicated that the Child-Pugh score significantly influenced the threshold dose, with median values of 51.6 Gy for Child-Pugh class A patients and 27.0 Gy for class B patients, while the number of treatment fractions did not show a significant effect.
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Article Synopsis
  • * Study involved 52 adults with no liver or kidney disease, using various imaging methods to compare fat estimates in the liver.
  • * Results showed MRI-PDFF (0.95 correlation) is significantly more accurate than US-HRI (0.38 correlation) for diagnosing fatty liver disease, indicating MRI-PDFF as the preferred method.
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Objectives: To evaluate the effect of abolishing instructions to fast prior to contrast-enhanced CT on acute adverse reactions (AARs).

Methods: In our institution, we instructed patients to fast one meal before contrast-enhanced CT examinations. However, we abolished these instructions at the end of March 2019, and solid food intake was not restricted before contrast-enhanced CT after this date.

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The purpose of this study was to improve the contrast between the nerves and blood by reconsidering the imaging parameters of the sampling perfection with application-optimized contrasts using different flip angle evolutions (SPACE) method, and to compare it with conventional methods, including the constructive interference in steady state (CISS) and T-weighted SPACE (T2-SPACE) methods. In the phantom study, the repetition time (TR), echo time (TE), flip angle (FA), and turbo factor (TF) of SPACE were varied using the restore pulse. The parameters for which the nerve-blood contrast (C1) and cerebrospinal fluid-nerve contrast (C2) were equal were selected.

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Purpose: To propose a new strategy to prevent communication errors caused by unread radiology reports.

Materials And Methods: Medical emergencies were prefixed with triple stars on radiology reports, and the attending physician was contacted by telephone. Semi-emergencies (medical issues needing addressing within 2 weeks) were prefixed with double stars.

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Objective: Detectable serum thyroglobulin (Tg) in patients with differentiated thyroid carcinoma (DTC) after total thyroidectomy indicates progression of the disease. Thyroglobulin doubling-time (TgDT) is a powerful prognostic predictor in patients with DTC. We aimed to evaluate the value of the dynamic TgDT for early detection of progressive disease (PD) in the patients of metastatic DTC with I radioactive iodine (RAI) therapy.

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Purpose: Prognostic significance of volumetric F-fluorodeoxyglucose (FDG) positron emission tomography/computer tomography (PET/CT) parameters in carbon-ion radiotherapy (C-ion RT) treated stage I non-small cell lung cancer, and need of histology-wise separate cut-off values for risk stratification were assessed.

Methods: Thirty-nine patients (29 men and 10 women, 71.9 ± 8.

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Objectives: L-3-[F]-Fluoro-α-methyl tyrosine (FAMT), an amino acid positron emission tomography (PET) tracer, complements [F]-fluorodeoxyglucose (FDG) in the diagnosis of malignancies. We compared the predictive ability of FAMT PET versus FDG PET regarding metastatic oral squamous cell carcinoma (OSCC) outcomes for distant metastasis, including lymph node metastasis, and identified the relevant metabolic parameters for each.

Methods: We enrolled 160 patients with OSCC who underwent PET/computed tomography using FDG and FAMT before treatment.

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F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is usually used to screen malignancy in patients with dermatomyositis (DM). Additionally, it is well known that FDG-PET/CT provides valuable information for evaluating the activity of several inflammatory diseases, such as sarcoidosis, atherosclerosis, inflammatory bowel disease and rheumatoid arthritis. Therefore, the objective of this study was to evaluate the clinical usefulness of FDG-PET/CT for the detection of inflammatory lesions and disease activity of both myopathy and interstitial lung disease (ILD) in DM patients.

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Article Synopsis
  • The study examined the effectiveness and safety of combining uterine artery embolization (UAE) with dilation and curettage (D&C) to treat cesarean scar pregnancy (CSP).
  • Researchers analyzed outcomes from 33 patients, focusing on factors like normalization of beta-hCG levels, hospitalization duration, menstruation resumption, and pregnancy success post-treatment.
  • The results showed that the treatment was mostly successful and safe, with 43.8% of those wishing to conceive achieving healthy pregnancies, suggesting it could be a viable option for preserving fertility.
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Objective: Bone scintigraphy (bone scan) is useful in detecting metastatic bone lesions through visual assessment of hot spots. A semi-quantitative analysis method that evaluates bone scan images has been eagerly anticipated. BONENAVI is software that enables automatic assessment of bone scan index (BSI).

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Rationale And Objectives: Our goals were to apply perfusion CT technique to breast tumor and to evaluate the correlation between arterial perfusion value and other tumor characteristics.

Materials And Methods: Thirty-one female patients with primary breast tumors were included in this study. A single-slice dynamic CT was performed after an intravenous bolus injection of contrast material (40 ml; 370 mg I/ml) at 8 ml/sec.

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Rationale And Objectives: We sought to determine the relationship between tumor blood flow and glucose uptake in head and neck tumors using perfusion computed tomography (PCT) and fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET).

Materials And Methods: Institutional review board approval and informed consent were obtained for this study. Sixteen patients (mean age, 67 years; age range, 36-89 years) who had known or suspected head and neck tumors (15 malignant tumors and one schwannoma) underwent PCT and FDG PET examinations.

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Air embolism is a rare but potentially fatal complication of percutaneous needle biopsy of the lung. We report a case of cerebral air embolism which occurred during computed tomography (CT)-guided needle biopsy. Air entering the aorta is depicted on CT-fluoroscopy images of the procedure.

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