Compared with cystectomy, is ovarian vaporization of endometriotic cysts truly more effective in maintaining ovarian reserve?

Study Objective: To evaluate how endometriotic cystectomy and vaporization affect ovarian reserve after conservative surgery.

Design: Prospective study (Canadian Task Force classification II-1).

Setting: Hokusetsu General Hospital.

The expression status of G protein-coupled receptor GPR30 is associated with the clinical characteristics of endometriosis.

Introduction: GPR30 is a seven-transmembrane G protein-coupled estrogen receptor that regulates endometrial cellular responses to estrogen. GPR30 is often highly expressed in cancer cells from aggressive tumors. The aim of this study was to evaluate the expression patterns of GPR30 in endometriosis during medical treatment.

Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis.

Background: The resistance of endometriotic tissue to progesterone can be explained by alterations in the distribution of progesterone receptor (PR) and estrogen receptor (ER) isoforms. The aims of this study were to examine the expressions of PR-A, PR-B, ERα and ERβ in endometrioma and assess whether these expressions are affected by dienogest or leuprolide acetate (LA) treatment.

Methods: We enrolled 60 females, including 43 patients with endometriosis (14 who received no medical treatment, 13 who received dienogest and 16 who received LA before undergoing laparoscopic surgery) and 17 patients with leiomyoma.