Publications by authors named "Hiroko Yamamoto-Oka"
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Synopsis of recent research by authors named "Hiroko Yamamoto-Oka"
- Hiroko Yamamoto-Oka's research primarily focuses on the mechanisms of inflammation and fibrosis in pulmonary diseases, particularly the roles of macrophages and fibroblasts in these processes.
- Recent findings suggest that pirfenidone can significantly suppress the proliferation of lung fibroblasts and inhibit the polarization of macrophages to the pro-fibrotic M2 phenotype, indicating its potential therapeutic benefits beyond its current clinical application.
- Additionally, the research explores the modulation of the M1/M2 macrophage phenotype by carbon monoxide-releasing molecule-3 (CORM-3), highlighting the importance of balancing these macrophage types in inflammatory responses and potential treatments for lung conditions.
