Publications by authors named "Hiroko Miyazato"
Article Synopsis
- The study aims to evaluate different diagnostic methods for detecting Clostridioides difficile infection (CDI) in patients with significant diarrhea across 12 medical facilities in Japan, comparing them to the gold standard of toxigenic culture (TC).
- Key findings indicated that nucleic acid amplification tests (NAAT) showed higher sensitivity (74%) compared to enzyme immunoassays (EIA) (41%) and performed similarly to the GDH algorithm (71%).
- Overall, NAAT and the GDH algorithm demonstrated good negative predictive values (92% and 91%, respectively) but highlighted the complexity of choosing the optimal diagnostic approach amid varying performance metrics for CDI detection.
Clostridioides (Clostridium) difficile is the leading cause of healthcare-associated infectious diarrhea in the developed world. Retrospective studies have shown a lower incidence of C. difficile infection (CDI) in Japan than in Europe or North America.
View Article and Find Full Text PDFEnterobacteriaceae producing extended spectrum β-lactamase (ESBL) are distributed worldwide. In this study, 114 ESBL-producing Enterobacteriaceae were isolated by analyzing 1672 clinical isolates of Enterobacteriaceae collected from an Okinawa prefectural hospital in Japan between June 2013 and July 2014. The overall prevalence of ESBL-producing Enterobacteriaceae was 6.
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