Case report: Five patients with myocarditis after mRNA COVID-19 vaccination.

Objectives: To describe clinical features and laboratory data of myocarditis after the mRNA COVID-19 vaccine in children.

Methods: We reviewed patients younger than 18 years of age, who visited our hospital because of myocarditis within 1 week after BNT162b2 from June 2021 to January 2022.

Results: We identified five male patients aged 12-16 years who presented to our hospital with myocarditis within 2-3 days after the second dose of BNT162b2 COVID-19 vaccination between June 2021 and January 2022.

Multiple evanescent white dot syndrome following vaccination for COVID-19: A case report.

Rationale: Multiple evanescent white dot syndrome (MEWDS) is an acute, usually unilateral, retinal disorder of unknown etiology that predominantly occurs in healthy young women. We report a case of bilateral asymmetric MEWDS that developed following the first vaccination for coronavirus-19 and worsened after a second vaccination.

Patient Concerns: A 30-year-old Japanese woman was examined in an eye clinic for blurred vision in her left eye for 1 week duration.

Clinical and Genetic Features of Tubulointerstitial Nephritis and Uveitis Syndrome with Long-Term Follow-Up.

Purpose: To investigate the clinical manifestations, prognosis, and HLA-type of tubulointerstitial nephritis and uveitis syndrome (TINU) with long-term follow-up.

Methods: Clinical data of five patients with TINU were retrospectively reviewed.

Results: The mean age was 15.

Long-term use of a once-a-day fentanyl citrate transdermal patch in lung cancer patients.

Transdermal fentanyl is widely administered as an analgesic therapy for cancer patients. Recently, a novel fentanyl citrate transdermal patch was developed in Japan, which is the first such patch that requires changing only once a day. The patch releases more stable serum fentanyl concentrations and results in less frequent adverse skin symptoms compared with the conventional 72-h transdermal fentanyl patch.

Cascading time evolution of dissipative structures leading to unique crystalline textures.

This article reports unique pattern formation processes and mechanisms via crystallization of materials under external flow fields as one of the general problems of open nonequilibrium phenomena in statistical physics. The external fields effectively reduce step-by-step the exceedingly large free energy barriers associated with the reduction of the enormously large entropy necessary for crystallization into unique crystalline textures in the absence of the fields. The cascading reduction of the free energy barrier was discovered to be achieved as a consequence of a cascading evolution of a series of dissipative structures.

Discrepancy of in-vitro data and clinical efficacy of micafungin against Candida tropicalis endophthalmitis.

We report findings for a 74-year-old woman with Candida tropicalis endophthalmitis for whom an increase in b-D-glucan level and worsening of endophthalmitis were observed after intravenous injection of micafungin, an echinocandin antifungal agent. Endogenous endophthalmitis caused by C. tropicalis developed in both eyes.

Identification and sensitivity of two rare fungal species isolated from two patients with Fusarium keratomycosis.

We report two cases of Fusarium keratomycosis in which molecular analysis was used to identify two rare causative Fusarium species. A 65-year-old woman was diagnosed with Fusarium keratomycosis caused by F. equiseti, confirmed by sequencing the internal transcribed spacer (ITS) region and morphological characteristics.

[A case of eosinophilic pneumonia which occurred after bone marrow transplantation for acute myeloid leukemia].

A 37-year-old woman with acute myeloid leukemia received allogeneic bone marrow transplantation (BMT) after systemic chemotherapy and total body irradiation. Soon after BMT both cutaneous and gastrointestinal graft-versus-host disease (GVHD) developed, but she was successfully treated with corticosteroids and tacrolimus. Thereafter, about 6 months after BMT a dry cough developed, and chest computed tomography (CT) showed a consolidated shadow in the right lower lobe which was resistant to antibiotics, and we finally diagnosed eosinophilic pneumonia based on a bronchoalveolar lavage analysis of the eosinophilia.

[An eight-year review of sensitivity to antimicrobials against isolated microorganisms from ocular infections].

Objective: To obtain data beneficial for future treatment by observing the circumstances relating to microorganisms isolated in external ocular infections and drug sensitivity, along with changes in drug-resistant bacteria.

Subjects And Methods: For an eight-year period from April 1998 to March 2006, the cultivation and identification of secretions from conjunctival sac and drug sensitivity tests were conducted at JA Gifu Koseiren Chuno General Hospital involving 3,876 patients (1,809 males and 2,067 females; average age: 44.2 +/- 29.

Effects of corneal thickness on intraocular pressure measured with three different tonometers.

Purpose: To compare intraocular pressure (IOP) measured by a Goldmann applanation tonometer (GAT), a noncontact tonometer (NCT), and a portable noncontact tonometer (PNCT) in eyes of healthy volunteers, and to determine if a significant correlation exists between the IOP and the central corneal thickness (CCT).

Methods: A total of 144 healthy participants were randomly assigned to one of two groups; in the first group, IOP was measured first with the NCT and then with the GAT. In the second group, IOP was measured first with the PNCT and then with the GAT.

Detection of staphylococcus species by polymerase chain reaction in late-onset endophthalmitis after cataract surgery and posterior capsulotomy.

We report a case of late-onset endophthalmitis that developed 5 years after an uneventful phacoemulsification with implantation of a posterior chamber intraocular lens. Posterior capsulotomy was performed with by Nd:YAG laser 1 month after the cataract surgery. Polymerase chain reaction with agarose gel electrophoresis identified a Staphylococcus species in a sample from the aqueous humour.

Improvement of scotopic electroretinograms and night blindness with recovery of serum zinc levels.

Background: We sought to determine the cause of reduced scotopic and photopic electroretinograms (ERGs) and night blindness in a 46-year-old man with liver dysfunction but no history of alcoholism.

Case: A 46-year-old Japanese man with a complaint of visual difficulties in dim light for 1 month.

Observations: By electrophysiological investigation, the patient was found to have low levels of serum zinc and vitamin A on admission.