Multi-focusing surface-emitting lasers.

Complete control of a beam pattern requires not only projecting a two-dimensional (2D) pattern but also focusing on a three-dimensional (3D) point cloud, which is typically achieved utilizing holography under the framework of diffraction. We previously reported direct focusing from on-chip size surface-emitting lasers that utilize a holographically modulated photonic crystal cavity based on 3D holography. However, this demonstration was of the simplest 3D hologram with a single point and single focal length, and the more typical 3D hologram with multiple points and multiple focal lengths has not yet been examined.

On-chip size, low-noise fringe pattern projector offering highly accurate 3D measurement.

Fringe pattern projectors are quite useful for highly accurate three-dimensional (3D) measurement when a projector or LED array is used for illumination. We have fabricated a 0.2 mm × 0.

Direct-focusing surface-emitting laser.

Focusing is a fundamental optical technique that has been widely implemented via lenses. Here, we demonstrate direct focusing from a band-edge surface-emitting laser, whose emission area is 200 µm × 200 µm, without any lenses. To achieve this, a phase-modulating layer is incorporated into the laser cavity.

200×200 µm structured light source.

3D structured illumination is important in high-speed 3D metrology where beam patterns are roughly categorized into multi-dot and fringe patterns. For example, large-scale multi-dot patterns are utilized for facial recognition in an iPhone X on the basis of an active stereo method, while fringe patterns are utilized in Grey code patterns or fringe projection profilometry including Fourier transform profilometry and the phase shifting profilometry, which is suitable for high-resolution measurement. Among these applications, the light sources include a combination of vertical-cavity surface-emitting lasers (VCSELs) and diffractive optical elements (DOEs), a projector, and so on.

Observational retrospective single-centre study in Japan to assess the clinical significance of serum daptomycin levels in creatinine phosphokinase elevation.

What Is Known And Objective: Daptomycin-induced creatinine phosphokinase (CPK) elevation is reported to be associated with its trough level (C ; breakpoint of 24.3 μg/mL). However, even with high-dose treatment (ie, > 8 mg/kg), the safety of daptomycin treatment is widely demonstrated with low or no significant incidence of CPK elevation or other adverse effects, despite the possibility of C above 24.

Disseminated cryptococcosis in a patient taking tocilizumab for Castleman's disease.

Infections occur more frequently in patients receiving biologics. However, cryptococcal infection is uncommon in patients receiving tocilizumab, an interleukin-6 inhibitor, in contrast to patients receiving tumor necrosis factor-α inhibitors. In this report, we describe a case of disseminated cryptococcosis in a 55-year-old man who was receiving tocilizumab every 2 weeks along with daily prednisolone and cyclosporine for Castleman's disease.

Capnocytophaga canimorsus bacteremia presenting with acute cholecystitis after a dog bite.

Capnocytophaga canimorsus is part of normal gingival flora of dogs and cats. The organism can cause septicemia, meningitis, and endocarditis in humans after contact with dogs or cats. In spite of the frequency of gastrointestinal symptoms in C.