Publications by authors named "Hiroki Ejiri"

Background: Malnutrition, evaluated by nutritional indices, is reportedly related to a poor prognosis in patients with hypertension. However, clinical evidence on which index is more suitable for predicting a kidney prognosis is limited, and it has not been evaluated in hypertension. The aim of the present study was to investigate and compare the predictive values of four nutritional indices: Geriatric Nutritional Risk Index (GNRI); Prognostic Nutrition Index (PNI); Triglycerides × Total cholesterol × Body weight Index (TCBI); and the controlling nutritional status (CONUT) score.

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Article Synopsis
  • A higher resting heart rate is identified as a risk factor for increased mortality and cardiovascular events in the general population, but its impact on patients with non-dialysis-dependent chronic kidney disease (CKD) is less understood.
  • A study involving 1,353 participants looked at the relationship between resting heart rate and adverse health outcomes over an average period of 4.9 years, focusing on all-cause mortality and cardiovascular events.
  • The results showed that participants with resting heart rates of 80-90 beats per minute and above 90 had significantly higher risks of all-cause mortality compared to those with heart rates below 70, highlighting an important health concern for CKD patients.
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Malnutrition is reportedly associated with adverse clinical outcomes in various populations. However, associations between nutritional status and adverse outcomes in patients with hypertension have not been sufficiently elucidated. We therefore aimed to investigate the impact of nutritional status as evaluated by the Geriatric Nutritional Risk Index (GNRI) on adverse outcomes in patients with hypertension.

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Article Synopsis
  • The study aimed to predict changes in kidney function among patients with chronic kidney disease (CKD) using advanced analysis methods, focusing on non-dialysis dependent individuals with an estimated glomerular filtration rate (GFR) of at least 45 mL/min/1.73 m² over five years.
  • Researchers classified 780 participants into five distinct groups based on their estimated GFR trajectories during the study, with significant declines observed in all classes, especially the fifth class, which experienced a 45.1% decrease.
  • Key factors influencing the prediction of kidney function decline included baseline estimated GFR, hemoglobin levels, and body mass index, indicating that a baseline GFR close to
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