Publications by authors named "Hirokazu Suii"
Article Synopsis
- The study compares the effectiveness of cell-free and concentrated ascites reinfusion therapy (CART) and large-volume paracentesis (LVP) with albumin infusion in treating refractory ascites (RA) in patients with cirrhosis.
- From June 2018 to March 2022, 25 patients were monitored for treatment outcomes, focusing on the number of paracenteses, drainage volume, and albumin use over 8 weeks.
- Results showed that while CART required fewer paracenteses and albumin infusions, there were no significant differences in overall treatment effectiveness, suggesting both therapies are equally beneficial for managing RA.
Introduction And Objectives: Sustained virologic response (SVR) is achieved in most cases of C-type liver disease after direct-acting antiviral (DAA) therapy. Although liver fibrosis improves, the degree of improvement is different. This study aimed to analyze the factors involved in improving liver fibrosis using the fibrosis 4 (FIB-4) index.
View Article and Find Full Text PDFObjective This study evaluated the efficacy associated with switching to rifaximin in patients with hepatic cirrhosis receiving kanamycin sulfate for the treatment of hepatic encephalopathy and hyperammonemia. Methods We included 37 patients who switched from kanamycin sulfate to rifaximin at our institution from January 2017 to December 2018. The onset of hepatic encephalopathy and changes in blood ammonia values during a six-month period were retrospectively evaluated.
View Article and Find Full Text PDFBackground And Aim: Since the advent of direct-acting antiviral (DAA) therapy, the total eradication of hepatitis C virus has been achievable with the recovery of hepatic reserve after achievement of sustained virologic response (SVR). Hence, here, we examined the factors affecting the recovery of hepatic reserve.
Methods: We followed up 403 patients (male: 164, female: 239; genotype 1: 299, genotype 2: 104; median age: 69 years) for at least 3 years after they achieved SVR to DAA therapy.
Article Synopsis
- This study investigated the link between low serum zinc levels and common symptoms in patients with chronic liver disease.
- A total of 578 patients were assessed, with 193 (33.4%) reporting symptoms like taste disorders, mouth sores, skin issues, hair loss, and loss of appetite.
- The findings revealed that as serum zinc levels fell, the occurrence of these symptoms increased, particularly noting a strong association between dermatitis and low zinc levels.
The recently approved direct-acting antivirals (DAA) agents are effective in terms of sustained virologic response (SVR) rates and are well tolerated in most hepatitis C virus (HCV) patients. This study aimed to analyze the association between serum zinc levels in patients who developed hepatocellular carcinoma (HCC) following HCV eradication after DAA treatment. The retrospective study included 769 HCV-infected patients who achieved SVR after DAA treatment.
View Article and Find Full Text PDFPurpose: This study aimed to reveal characteristic imaging features of bile duct adenoma (BDA) by radiologic-pathologic correlation.
Materials And Methods: We retrospectively analyzed pathological and imaging findings of seven patients with BDA.
Results: The median maximum diameter of BDA was 5.
Aim: This study aimed to determine the distributions of serum zinc levels and the prevalence of zinc deficiency in patients with chronic liver disease (CLD) in actual clinical practice, and to analyze the association between serum zinc levels and clinical characteristics.
Methods: This study analyzed 1973 patients with CLD, including 749 with liver cirrhosis, who were admitted to Sapporo Kosei General Hospital in 2017.
Results: Zinc deficiency, defined as a serum zinc level of <60 μg/dL, was observed in 555 patients overall (28.
Aim: In Japan, no zinc preparation had been approved for therapeutic purposes before March 2017. Zinc acetate hydrate was recently approved for the treatment of hypozincemia. We evaluated the efficacy and safety of treatment with zinc acetate hydrate.
View Article and Find Full Text PDFInterferon (IFN) and ribavirin (RBV) combination therapy was previously the standard of care for treatment of hepatitis C virus (HCV) genotype 2 infection. But, it often induced hemolytic anemia. In 2014, sofosbuvir (SOF) was approved for the treatment of chronic HCV genotype 2 in Japan.
View Article and Find Full Text PDFAim: We investigated the utility of high-sensitivity hepatitis B surface antigen (HBsAg) assays compared with conventional HBsAg assays.
Methods: Using serum samples from 114 hepatitis B virus (HBV) carriers in whom HBsAg seroclearance was confirmed by conventional HBsAg assays (cut-off value, 0.05 IU/mL), the amount of HBsAg was re-examined by high-sensitivity HBsAg assays (cut-off value, 0.