Publications by authors named "Hirofumi Nakahari"
Purpose: The influence of anesthetic interactions on motor-evoked potentials in infants has rarely been reported. In infants, adding a small dose of sevoflurane to propofol-based total intravenous anesthesia is reasonable for reducing propofol administration. We collected preliminary data regarding the effect of low-dose sevoflurane in propofol-based total intravenous anesthesia on motor-evoked potentials in infants.
View Article and Find Full Text PDFModified thoracoabdominal nerve block through the perichondrial approach (M-TAPA) is a novel strategy for peripheral nerve block in the abdomen. Its usefulness has been highlighted in adults, but no literature is currently available regarding its efficacy in infants. This report describes the cases of a one-day-old neonate in open abdominal surgery and a one-month-old infant in laparoscopic surgery who received M-TAPA.
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- The study investigates how low-dose sevoflurane combined with propofol-based total intravenous anaesthesia (TIVA) affects motor-evoked potentials (MEP) in infants undergoing spinal surgery, as infants are more sensitive to anaesthetics, which could impact nerve function.
- Conducted at a children's hospital in Japan from July 2024 to June 2029, the randomized controlled trial will enroll infants aged 35 to 87 weeks, measuring MEP amplitudes before and after anaesthesia to identify any significant changes between a group receiving the sevoflurane and one that does not.
- The study has received ethical approval and aims to ensure safety and efficacy in neur
Motor-evoked potential (MEP) monitoring is commonly used in children. MEP monitoring in infants is difficult due to smaller signals requiring higher stimulation voltages. There is limited information on the effect of different anesthetics on MEP monitoring in this age group.
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- Intraoperative neurophysiological monitoring helps prevent spinal cord and nerve injuries during surgeries in neonates and infants, but poses challenges due to their developing nervous systems needing higher stimulation voltages.
- Administering lower anesthesia doses to ensure adequate signals can lead to unexpected movements if neuromuscular blockers aren't used, complicating surgical procedures.
- The review discusses current anesthetic options and the unique challenges faced in monitoring anesthetic depth in infants and neonates, highlighting the importance of understanding age-specific physiological differences for anesthesiologists.