Publications by authors named "Hirofumi Kimoto"
Article Synopsis
- About 8-10% of newborns with asymptomatic congenital cytomegalovirus (cCMV) infection develop sensorineural hearing loss (SNHL), prompting a study to investigate the links between CMV load, SNHL, and central nervous system (CNS) damage.
- The study analyzed 23,368 newborns in Japan, screening for cCMV infection via urine tests and assessing hearing through automated auditory brainstem response (AABR) testing.
- Findings indicated a low incidence of cCMV (0.257%), with a notable 22.7% of infants with SNHL also infected with cCMV; higher urinary CMV loads were linked to both SNHL and CNS damage as
Background: The aim of the present study was to assess 3 year auditory and neurodevelopmental outcomes of persistent pulmonary hypertension of the newborn (PPHN) before and after introducing inhaled nitric oxide (i-NO) therapy, and to detect the clinical factors affecting poor outcome.
Methods: A retrospective historical cohort study of 26 survivors with PPHN with oxygenation index (OI) >or=25 (13 infants without i-NO therapy, control group; 13 with i-NO therapy, i-NO group) was performed. Auditory brainstem response (ABR) at 6 and 12 months and neurodevelopmental outcomes at 3 years of age were evaluated.
Article Synopsis
- The study aimed to identify factors that predict survival in premature infants born at 23-24 weeks of gestation.
- A retrospective analysis was conducted on 92 infants admitted to a specialized neonatal unit, with survival defined as being discharged from the unit.
- Key predictive factors for survival included systolic blood pressure, ventilatory index, initial hemoglobin level, and base excess within the first 6 hours after birth.
In a case control study, we evaluated the serum lactate levels during the early days of life in preterm infants with periventricular leukomalacia (PVL), who were presumed to have suffered injury around birth. Thirteen infants diagnosed by ultrasonography as suffering from cystic PVL during the neonatal period and 26 normally developed infants matched by gestational age were enrolled in the study. The serum lactate level was measured repeatedly during the 72 h after birth.
View Article and Find Full Text PDFAim: To determine whether inhaled nitric oxide might reduce the need for excessive respiratory alkalosis to maintain systemic oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN).
Materials And Methods: A retrospective historical cohort study of 34 infants with PPHN with oxygenation index (OI) of 25 or more, including 19 infants without inhaled nitric oxide (i-NO) therapy (control group) and 15 infants with inhaled nitric oxide therapy (i-NO group) was performed. The initial dose of 10 ppm of i-NO was administered and no responders received the maximum dose of 25 ppm.
Background: The purpose of the present paper was to evaluate the mortality and morbidity of infants born at 22-24 weeks gestation.
Methods: A total of 78 infants born at 22-24 weeks gestation, who were admitted between January 1991 through December 2000, were retrospectively studied.
Results: Seventy-one of 78 infants were enrolled in the present study.
Background: Several authors reported that there was a close relationship between unbound bilirubin concentrations and abnormal results of auditory brainstem responses. Full-term infants with high-unbound bilirubin concentrations who were treated with human albumin were followed to evaluate their hearing abilities by using auditory brainstem responses.
Methods: Fifty-eight infants (gestational age, 39.