Peripheral nerve conduction abnormalities precede morphological alterations in an experimental rat model of sepsis.

Purpose: The pathological mechanisms of critical illness polyneuropathy (CIP), an acute neuromuscular disorder, remain unknown. In this study, we evaluated nerve and vascular properties that might account for electrophysiological abnormalities, including reduced nerve conduction amplitude, in the early phase of CIP.

Methods: Rats were administered intravenous saline (C-group; n = 31) or lipopolysaccharide (3 mg/kg/day; L-group; n = 30) for 48 h.

Thrombomodulin improves maternal and fetal conditions in an experimental pre-eclampsia rat model.

Aim: The aim of this study was to investigate whether the consecutive administration of recombinant thrombomodulin (r-TM) for 4 days improves maternal and fetal conditions and physiological outcomes in an N'-nitro-L-arginine-methyl ester hydrochloride-induced and low-dose endotoxin-induced pre-eclampsia (PE).

Methods: r-TM or saline was administrated i.v.

[Unexpectedly complicated laryngoscopy caused by a massive mandibular tori].

Here, we report a case of an unexpectedly complicated laryngoscopy caused by massive mandibular tori. A 64-year-old man with mitral regurgitation and aortic regurgitation was scheduled for a double valve replacement. Thyromental distance and the Mallampati score were used as predictive factors of difficult intubation, and both factors were within the normal range.

[Case of laparoscopic cholecystectomy in a patient with glucose-6-dehydrogenase deficiency].

We report management of anesthesia in a patient suffering from glucose-6-phosphate dehydrogenase (G6PD) deficiency, a condition that induces acute hemolysis when associated with surgical stress and infection, or following the application of oxidant drugs. A 5 year-old-male patient, suffering from G6PD deficiency was scheduled for laparoscopic cholecystectomy. The patient had exhibited signs of hemolysis during the course of various infections and after ingesting fava beans (favism).

[Two cases of intraoperative cerebral hemorrhage caused by undiagnosed metastatic brain tumors].

The authors report two cases of intraoperative cerebral hemorrhage caused by metastatic brain tumors. Delayed recovery from general anesthesia and neurological deficit were found in these patients. Brain CT in case 1 showed bilateral subdural hemorrhage and parenchymal massive hemorrhage in case 2.