Publications by authors named "Hirofumi Aotani"
Early inhaled steroid use in extremely low birthweight infants: a randomised controlled trial.
Arch Dis Child Fetal Neonatal Ed
November 2016
Objective: We hypothesised that a prophylactic inhaled steroid would prevent the progression of bronchopulmonary dysplasia (BPD) in extremely low birthweight infants (ELBWIs).
Design: This study was a multicentre, randomised, double-blinded, placebo-controlled trial.
Setting: This investigation was conducted in 12 level III neonatal intensive care units (NICUs).
A neonatal case of provisional neurocutaneous melanosis presenting with lissencephaly is reported. Several congenital nevi were observed on the trunk and extremities of the infant, including a giant congenital hairy nevus over the skull. Brain magnetic resonance imaging revealed a marked ventricular dilatation with pachygyria and an absent corpus callosum; however, an injection of gadolinium did not demonstrate any enhanced lesions.
View Article and Find Full Text PDFObjectives: The objectives of this study were to describe the characteristics and morbidity of very low birth weight infants, to identify the medical intervention for these infants, and to evaluate the factors affecting the mortality of these infants among the participating hospitals.
Methods: A large multicenter neonatal research network that included level III NICUs from throughout Japan was established. A standardized mortality rate was formulated by giving a ratio of the observed deaths and the predicted deaths based on a 100-g birth weight interval mortality.
We report a neonatal case of Peters' anomaly with bilateral perisylvian polymicrogyria and abdominal calcification. The male infant was born after a normal labor. Bilateral central corneal opacities with iridocorneal strands indicated Peters' anomaly.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess the effectiveness of the minor neurological signs test (MNT) as a predictor for attention deficit hyperactivity disorder (ADHD) and hyperactivity disorder (HD) in children at 4-6 years old who had perinatal risks.
- Research was conducted on 136 children who were previously in neonatal intensive care, analyzing their MNT scores alongside established ADHD and HD diagnostic criteria.
- Results indicated that MNT scores strongly correlated with ADHD and HD diagnoses, achieving a diagnostic validity of 78% sensitivity and 79% specificity, while also revealing key risk factors affecting behavioral outcomes in relation to the children's birthweight.
Objective: To delineate clinical features of a case of fetal hemolytic disease due to anti-Rh17, along with a review of relevant studies published in English and Japanese.
Methods: We present clinical features of a -D-/-D- phenotype woman with anti-Rh17 alloimmunization during pregnancy. Relevant English literature in the MEDLINE database was reviewed, while Japanese studies were searched in the Japana Centra Revuo Medicina database.