Clinical outcomes of MII oocytes with refractile bodies in patients undergoing ICSI and single frozen embryo transfer.

Purpose: This study aimed to analyze whether the presence of refractile bodies (RFs) negatively affects fertilization, embryo development, and/or implantation rates following intracytoplasmic sperm injection (ICSI).

Methods: This retrospective embryo cohort study involved a total of 272 patients undergoing ICSI treatment of blastocyst cryopreservation.

Results: In the study, no significant differences were found regarding 2PN formation rates between RF(+) (76.

A higher incidence of smooth endoplasmic reticulum clusters with aromatase inhibitors.

Purpose: This study aimed to analyze whether a regimen of aromatase inhibitor (AI) could reduce the occurrence of smooth endoplasmic reticulum clusters (sERCs) in oocytes.

Methods: The AI and the clomiphene citrate (CC) regimens were compared, regarding the sERC (+) rates and the serum estradiol and progesterone levels on the date of hCG administration, and the duration of AI, CC, and hMG administration.

Results: The occurrence of sERCs in oocytes from patients treated with AI was significantly higher than that in oocytes from those treated with CC.