: This study aims to evaluate and compare the safety and efficacy of the da Vinci Xi and hinotori™ SRS robot-assisted surgical systems for gynecologic disorders. : We conducted a retrospective study of 401 cases (43 benign uterine tumors; 88 pelvic organ prolapses; 270 low-risk endometrial cancers) of robot-assisted surgery performed at Kagoshima University Hospital between January 2017 and October 2024. Surgical factors such as the operative time, blood loss, and complication rates were analyzed and compared between the da Vinci Xi (332 cases) and hinotori™ SRS (69 cases) systems.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Sodium croconate, a high-voltage organic cathode material, can be applied to high-energy-density and cost-effective organic sodium-ion batteries (OSIBs) as an alternative to traditional lithium-ion batteries. However, organic molecular cathodes generally dissolve into the electrolyte, leading to poor cyclability. Thus, an electrolyte that can address the present limitations and further facilitate the fabrication of highly reversible OSIBs must be developed.
View Article and Find Full Text PDFAn 87-year-old man with complaints of palpitations and digestive bleeding previously visited another hospital. He was referred to our hospital because of anemia. Small bowel endoscopy revealed an elevated lesion with bleeding from the ileum.
View Article and Find Full Text PDFIntroduction: To identify prognostic biomarkers that could predict how well patients will respond to lenvatinib/pembrolizumab (LEN/PEM). The utility of certain inflammatory biomarkers in endometrial liquid-based cytology (LBC) or peripheral blood samples, such as neutrophil counts, lymphocyte counts, and neutrophil-to-lymphocyte ratio (NLR) were explored.
Methods: The study included 25 patients with advanced or recurrent endometrial cancer who had received LEN/PEM between August 2018 and March 2024.
Background: The standard for robotic para-aortic lymphadenectomy has not been fully established. Para-aortic lymphadenectomy performed by sharing the same ports with pelvic procedures, a procedure known as dual-docking surgery, can be performed using the latest robotic system. We prospectively examined the ability of standardized dual-docking robotic surgery in endometrial cancer patients.
View Article and Find Full Text PDFObjectives: This study aimed to compare the surgical outcomes of simple hysterectomy with sentinel lymph node biopsy for low-risk endometrial cancer performed using the hinotori™ Surgical Robot System and the da Vinci® Xi system.
Materials And Methods: We retrospectively analyzed the data of 234 patients who underwent simple hysterectomy with sentinel lymph node biopsy at Kagoshima University Hospital between January 2017 and June 2024. Amongst them, 20 patients underwent surgery using the hinotori™ Surgical Robot System and 214 using the da Vinci® Xi.
Mol Ther Nucleic Acids
December 2024
infection has been associated with various systemic diseases and may cause delayed healing of muscle injury. However, the relationship between muscle injury healing and infection remains unclear. Our hypothesis was that infection delays the healing of muscle injuries.
View Article and Find Full Text PDFRechargeable aqueous zinc-ion batteries (RAZIBs) are attracting increasing attention due to their advantages in safety, cost, and energy density. However, the choice of electrode binders when using aqueous electrolytes faces many constraints, as nontoxic and low-cost hydrophilic binders, such as sodium alginate (SA), can lead to electrode damage due to excessive swelling in aqueous solution. Here, by employing double-network hydrogel electrolytes formed by poly(vinyl alcohol) and alginate, the content and activity of water molecules at the electrode-electrolyte interface are reduced, and the mechanical stability of the electrode is reinforced, thereby affording reliable protection to the cathode bonded with SA.
View Article and Find Full Text PDFMalignant peripheral nerve sheath tumors (MPNSTs) of the cervix are rare, particularly in patients with neurofibromatosis type 1 (NF1). This report describes a cervical MPNST in an 18-year-old patient with no history of sexual activity, abnormal vaginal discharge, and prolonged menstruation. She had more than six café-au-lait spots on her body since birth and was diagnosed with NF1 at 2 years of age.
View Article and Find Full Text PDFPhosphoglyceride crystal deposition disease is a rare condition occurring in soft tissues, resulting in scarring and affecting the bones, making preoperative differentiation from malignant tumors challenging. Here, we describe a case of phosphoglyceride crystal deposition disease initially suspected to be a malignant ovarian tumor before surgery. A 50-year-old woman with a history of three cesarean sections presented with lower abdominal pain.
View Article and Find Full Text PDFPurpose: Stress urinary incontinence is a postoperative complication occurring in patients with pelvic organ prolapse (POP). Although the 1-hour pad test measures the degree of urinary incontinence qualitatively and quantitatively, some elderly women undergoing POP surgery do not have the daily activities of living to perform the pad test. Therefore, we examined whether the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) could be used as an alternative tool for pad tests.
View Article and Find Full Text PDFBackground: Prognostic predictors of immunotherapy in patients with advanced endometrial cancer remain unclear. The potential role of inflammatory predictors, including pretreatment neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and hemoglobin, albumin, lymphocyte and platelet scores, was investigated.
Methods: Between August 2018 and December 2023, 35 patients were retrospectively analyzed.
Background: Sentinel lymph node navigation surgery, which identifies the sentinel lymph node in early cervical cancers and omits systemic pelvic lymphadenectomy in cases where no lymph node metastasis is present, has recently gained attention. However, there are few reports on lymph node recurrence and the long-term outcomes of cervical cancer surgery performed using sentinel lymph node navigation surgery. In this study, we aimed to evaluate the long-term outcomes of sentinel node navigation surgery for early-stage cervical cancer.
View Article and Find Full Text PDFAlthough exploratory laparoscopy in patients with advanced ovarian cancer is a diagnostic tool for determining treatment strategy, its safety has not been completely investigated. We report a case involving a severe abdominal abscess following an exploratory laparoscopy. A 65-year-old woman with advanced ovarian cancer developed a large abdominal abscess following exploratory laparoscopy and neoadjuvant chemotherapy.
View Article and Find Full Text PDFSerous tubal intraepithelial carcinoma, serous tubal intraepithelial lesions (STILs), and the p53 signature are considered to be related to precursor lesions of high-grade serous carcinomas (HGSCs). However, the clinical significance and prognostic implications of these lesion types are currently unknown. We diagnosed three patients with STILs according to the morphological evaluation criteria and combined this with p53 and Ki-67 immunostaining.
View Article and Find Full Text PDFRadical cystectomy after low anterior resection is rare, and no cases of robotic surgery have been reported. Cystectomy in patients who have undergone a previous pelvic surgery, whether open or endoscopic, requires caution to avoid damaging other organs due to anatomical changes caused by adhesions in a limited space. Additionally, the curative nature of the treatment must be maintained.
View Article and Find Full Text PDFIntroduction: NSCLC is a leading cause of cancer-related mortality worldwide. Specific genetic alterations, such as exon 14 (ex14) skipping, have been identified in NSCLC, allowing targeted therapy. Tepotinib, a highly selective MET inhibitor, has displayed promise in patients with advanced NSCLC.
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