Publications by authors named "Hira Waseem"

Objective: To assess the impact of educational intervention on nurse's knowledge related to patient safety after cardiac catheterisation in tertiary care settings.

Methods: The quasi-experimental study was conducted from October 2022 to May 2023 after approval from the ethics review board of Dow University of Health Sciences, Karachi, and comprised staff nurses working in cardiac catheterisation laboratory, cardiac care unit and allied departments of 4 tertiary care hospitals. After baseline assessment, those with knowledge score <70% were enlisted for educational intervention which was done in small groups and lasted about 120 minutes.

View Article and Find Full Text PDF

Opioid use disorder (OUD) remains a significant public health challenge with patients often facing barriers to initiating medications for opioid use disorder (MOUD). Traditional initiation methods for buprenorphine-naloxone (buprenorphine/naloxone) can be challenging due to the longer duration of transition and the risk of precipitated withdrawal. This manuscript presents a case series of four patients who successfully transitioned to buprenorphine/naloxone maintenance using a novel approach: low-dose intravenous (IV) buprenorphine initiation.

View Article and Find Full Text PDF

Objective: To assess the elasticity of placenta using shear wave elastography in normal and high-risk pregnancies in the third trimester.

Methods: The prospective, observational study was conducted at the Dow Institute of Radiology, Dow University of Health Sciences, Karachi, from September 15, 2022, to January 15, 2023, and comprised singleton pregnant women during 28-40 weeks of gestation who were referred from the obstetric department. The subjects were divided into normal pregnancy group A and high-risk pregnancy group B.

View Article and Find Full Text PDF

Background: Esophageal cancer is on a steady rise and carries significant mortality and morbidity. Depending upon the clinical stage at presentation, either chemotherapy, radiotherapy with or without surgical resection is the treatments in practice. Traditionally, open esophagectomy was performed but over time, the importance of minimally invasive esophagectomy has been established.

View Article and Find Full Text PDF

Objective: To investigate the relationship of serum homocysteine, folic acid, and vitamin-B12 levels with recurrent pregnancy loss (RPL).

Methods: A case-control study was conducted in the Department of Gynecology and Obstetrics, Dr. Ruth Pfau Civil Hospital, Karachi from July 2021 to June 2022.

View Article and Find Full Text PDF

Objective: To project total fertility rates for urban and rural areas in Pakistan up to 2027 with 80% prediction intervals.

Methods: The secondary-data study was conducted from March 2020 to August 2020 at Data Bank in the Department of Statistics, University of Karachi, Pakistan, and comprised publicly available data of the Pakistan Demographic Survey from 1984 to 2007. Two statistical models, the functional time series model and the coherent functional model, were used to make the predictions about age-specific fertility rates.

View Article and Find Full Text PDF

Musculoskeletal disorders (MSDs) have a high prevalence among allied health care providers because of the demanding nature of their work and lack of practicing proper ergonomics. The aim of this study focused on patterns of work-related musculoskeletal disorders (WMSDs) affecting different health care providers working in a different unit of a tertiary care hospital. This cross-sectional study collected data from 2000 allied health care providers working at various departments of Civil Hospital and Dow University Hospital of Karachi (DUHS), via self-administered questionnaire, based on Occupational Safety and Health Administration (OSHA) guidelines.

View Article and Find Full Text PDF

The successful outcome of allogeneic hematopoietic stem cell transplant (HSCT) in aplastic anemia patients is driven by suitable donor selection, appropriate conditioning regimen, early intervention, and optimal supportive care after transplant. Pakistan, being a developing country, faces grave economic challenges due to meager health care budget; therefore, cost constraints remain the foremost impediment in optimizing transplant facilities for socioeconomically deprived patients. We conducted a single-center retrospective analysis of aplastic anemia patients ( = 130), who received matched sibling donor transplants from 2011 to 2019, treated with either fludarabine/cyclophosphamide (Flu/Cy) or antithymocyte globulin/cyclophosphamide (ATG/CY) conditioning regimen.

View Article and Find Full Text PDF

Objective To compare the mean change in peak expiratory flow values in children receiving inhaled beclomethasone dipropionate versus inhaled budesonide in the treatment of mild persistent asthma. Method The medical records of 60 patients from the outpatient department (OPD)/emergency room (ER), National Institute of Child Health, Karachi, who received beclomethasone dipropionate (BDP) 200 µg one puff and budesonide (BUD) 200 µg one puff twice a day for treatment of mild persistent asthma from March 10, 2020, to August 10, 2020, were explored. Results The mean age of children was 10.

View Article and Find Full Text PDF

Objectives: Gastrointestinal stromal tumors (GISTs) are rare tumors of gastrointestinal tract, prognosis of which largely depends upon histopathologic characteristics of resection specimens, which were not widely studied in our population. Therefore we aimed to evaluate the histopathologic characteristics of GISTs in our population and their prognostic grouping according to college of American pathologist's guidelines.

Results: Mean age of patients was 53.

View Article and Find Full Text PDF

Objective: To determine the association of single-nucleotide polymorphism8nrg433E1006 in the neuregulin-1 gene associated with schizophrenia.

Methods: This case-control study was conducted at the Fountain House, Lahore, and the psychiatric clinics at the Aga Khan University, Karachi, from 2010 to 2013.The total genomic deoxyribonucleic acid was isolated and single-nucleotide polymorphism8nrg433E1006 was screened by nested polymerase chain reaction followed by sequencing.

View Article and Find Full Text PDF

Objective: To determine the knowledge,attitudes and practices of urban women regarding breast cancer and its available screening modalities.

Methods: The cross-sectional, questionnaire-based, descriptive study was conducted in the urban population of Karachi in November 2010. Female attendants (n=373) visiting a tertiary care centre and four of its urban outreach centres during the study period were administered a questionnaire.

View Article and Find Full Text PDF