Publications by authors named "Hira Peracha"
Background: Coping can moderate the relationship between trauma exposure and trauma symptoms. There are many conceptualisations of coping in the general population, but limited research has considered how autistic individuals cope, despite their above-average rates of traumatic exposure.
Objectives: To describe the range of coping strategies autistic individuals use following traumatic events.
Research on adults indicates other-oriented perfectionism (requiring perfection from others) is associated with various consequential outcomes independent of self-oriented perfectionism (requiring perfection of the self) and socially prescribed perfectionism (believing others require perfection of the self). However, historically, the most widely used and researched measure of trait perfectionism in children, the Child-Adolescent Perfectionism Scale (CAPS), has omitted other-oriented perfectionism. In the present study, we address this by reporting on the multisource development and validation of the first self-report measure of other-oriented perfectionism specifically intended for youths: the Other-Oriented Perfectionism Subscale-Junior Form (OOPjr).
View Article and Find Full Text PDFGlycosaminoglycans (GAGs), dermatan sulfate (DS), heparan sulfate (HS), and keratan sulfate (KS), are the primary biomarkers in patients with mucopolysaccharidoses (MPS); however, little is known about other biomarkers. To explore potential biomarkers and their correlation with GAGs, blood samples were collected from 46 MPS II patients, 34 MPS IVA patients, and 5 MPS IVB patients. We evaluated the levels of 8 pro-inflammatory factors (EGF, IL-1β, IL-6, MIP-1α, TNF-α, MMP-1, MMP-2, and MMP-9), collagen type II, and DS, HS (HS0S, HSNS), and KS (mono-sulfated, di-sulfated) in blood.
View Article and Find Full Text PDFArticle Synopsis
- - Mucopolysaccharidosis IVA (MPS IVA), also known as Morquio A syndrome, is an autosomal recessive disorder caused by a deficiency of the enzyme N-acetylgalactosamine-6-sulfate sulfatase, leading to the accumulation of specific glycosaminoglycans that affect cartilage and bone development.
- - Symptoms include short stature, spinal issues, respiratory problems, joint laxity, and various skeletal abnormalities, which are influenced by an imbalance in growth across bones and other tissues.
- - Diagnosis involves clinical assessments, imaging, and biochemical tests, specifically measuring glycosaminoglycans in urine and blood, alongside enzyme activity and molecular analysis, to differentiate MPS IVA from similar
The aim of this study was to obtain data about the epidemiology of the different types of mucopolysaccharidoses in Japan and Switzerland and to compare with similar data from other countries. Data for Japan was collected between 1982 and 2009, and 467 cases with MPS were identified. The combined birth prevalence was 1.
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