Publications by authors named "Hira Niaz"

Article Synopsis
  • - Acinetobacter baumannii is a significant cause of hospital-acquired infections worldwide, with its multidrug-resistant strains raising serious public health issues.
  • - Researchers isolated 30 MDR A. baumannii strains from clinical samples and studied the characteristics of a specific phage, vB_AbaS_SA1, including its genome and antibacterial properties.
  • - The phage demonstrated effective antibacterial action, especially when used alongside antibiotics, suggesting a promising phage-antibiotic synergy, although further research is needed to fully understand its mechanisms and limitations.
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One of the significant issues in treating bacterial infections is the increasing prevalence of extensively drug-resistant (XDR) strains of Acinetobacter baumannii. In the face of limited or no viable treatment options for extensively drug-resistant (XDR) bacteria, there is a renewed interest in utilizing bacteriophages as a treatment option. Three Acinetobacter phages (vB_AbaS_Ftm, vB_AbaS_Eva, and vB_AbaS_Gln) were identified from hospital sewage and analyzed for their morphology, host ranges, and their genome sequences were determined and annotated.

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