5 Slides in 5 Minutes: Incorporating CanMEDS Competencies on Acute Care Surgery.

Background: The University of British Columbia (UBC) Division of General Surgery developed an initiative entitled "5-in-5s" to improve educational opportunities on the Acute Care Surgery (ACS) service. We examined whether 5-in-5s are felt to be a valuable teaching tool, and evaluated their ability to incorporate CanMEDS competencies within the General Surgery program.

Methods: A web-based survey was distributed to all general surgery trainees and staff on ACS that have participated in 5-in-5s.

Rural trauma telementoring: a pilot project.

Background: Given Canada's geographically dispersed population, initial trauma care may occur at rural sites that may not manage patients with trauma frequently; thus, telementoring can play a life-saving role. In this article, we describe a rural trauma telementoring pilot program in British Columbia and report the results of an evaluation of its strengths and weaknesses.

Methods: Trauma surgeons from a quaternary trauma centre in Vancouver helped facilitate 3 in situ trauma simulation sessions at a rural BC hospital between fall 2019 and summer 2020.

Surgical training in the midst of a pandemic: a distributed general surgery residency program's response to COVID-19.

The coronavirus disease 2019 (COVID-19) pandemic has had a substantial impact on surgical training. We describe some of the challenges brought on by the pandemic and our program's province-wide response to them. We focus specifically on residents' provision of service, education and wellness.

Sclerotherapy for rectal prolapse in children: A systematic review and meta-analysis.

Background: Sclerotherapy is a commonly utilized treatment for rectal prolapse in children. This study systematically evaluates the effectiveness and complications of various sclerosing agents in treating pediatric rectal prolapse.

Methods: After protocol registration (CRD-42018088980), multiple databases were searched.

Stapled versus hand-sewn pediatric intestinal anastomoses: A retrospective cohort study.

Background: Whereas the adult literature has demonstrated the acceptable safety profile of stapled anastomoses when compared to the hand-sewn alternative, the choice of intestinal anastomosis using sutures or staples remains inadequately investigated in children. The purpose of this study is to compare the anastomotic outcomes of both techniques in children under 5years of age.

Methods: A retrospective analysis of patients undergoing intestinal anastomosis at a single tertiary centre (2012-2016) was undertaken.

The relationship between preoperative nutritional state and adverse outcome following abdominal and thoracic surgery in children: Results from the NSQIP database.

Introduction: Anthropometric measurements can be used to define pediatric malnutrition. Our study aims to: (1) characterize the preoperative nutritional status of children undergoing abdominal or thoracic surgery, and (2) describe the associations between WHO-defined acute (stunting) and chronic (wasting) undernutrition (Z-scores <-2) and obesity (BMI Z-scores >+2) with 30-day postoperative outcomes.

Methods: We queried the Pediatric NSQIP Participant Use File and extracted data on patients' age 29days to 18years who underwent abdominal or thoracic procedures.

Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial.

Background: Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism.

Methods: 62 children with autism recruited from 6 centers, ages 2-7 years (mean 4.

Simple and rapid detection of factor V Leiden by allele-specific PCR amplification.

Resistance to activated protein C is the most common hereditary cause for thrombosis and significantly linked to factor V Leiden. In this study, primers were designed to identify the factor V mutation by allele-specific PCR amplification. 126 patients with thromboembolic events were analysed using this technique, PCR-RFLP and direct sequencing.

The effect of methylene blue phototreatment on plasma proteins and in vitro coagulation capability of single-donor fresh-frozen plasma.

Background: Photodynamic virus inactivation of fresh-frozen plasma (FFP) may result in its impaired coagulation capability.

Study Design And Methods: Double-volume plasmapheresis samples from 11 donors were divided in pairs of 250 mL. One group underwent methylene blue (MB) phototreatment (MB-FFP).

Retrospective statistical analysis of coagulation parameters after 250 liver transplantations.

Extensive transfusion of blood components as a typical feature of OLT has been described by many authors. The perioperative requirement for transfusion, however, follows a downward trend, although the indications for OLT have been extended. Functional disturbances such as hyperfibrinolysis or platelet dysfunction, demonstrated by laboratory tests, such as platelet counts, PT, aPTT, TT, fibrinogen, and ATIII are often used to direct the transfusion of blood components, although preoperative data give insight only into the insufficient function of the old liver, which will be explanted and replaced by the donor graft.

Successful treatment of a patient with postpartum factor VIII inhibitor with recombinant human interferon alpha 2a.

A patient who had developed a postpartum inhibitor to factor VIII and who did not respond to repeated therapy with steroid and high-dose intravenous gammaglobulin G was treated with one short course of low-dose recombinant interferon alpha 2a (rhIFN) s.c. Within 7 weeks from the start of rhIFN treatment, the inhibitor disappeared.

[Homozygous infant in a family with hereditary protein C deficiency].

We report on a female infant homozygous for protein C deficiency in a Jordanian family with frequent intermarriage. A protein C antigen of 0.6% was determined.

[Determination of factor VIII-coagulation antigen in factor VIII concentrates using an inhibitor test].

The method of determination of factor VIII coagulation antigen (VIIICAg) here described is based on the well established factor VIII inhibitor test. Highly concentrated inhibitors to factor VIII in factor VIII substituted hemophiliacs are the most frequent among inhibitors to clotting factors. If such an inhibitor is used in an inhibitor assay its reaction depends on the VIIICAg concentration in the test system.

[Different proportions of factor VIII and factor VIII inhibitors in their antigen-antibody complexes].

We examined the physico-chemical properties of factor VIII inhibitors in two patients. There is no stoichiometric mixture of factor VIII and factor VIII inhibitor since one polyvalent factor VIII particle can be bound by various numbers of factor VIII inhibitor particles. The balance between free factor VIII and inhibitor and their antigen-antibody complexes cannot be explained by the homogeneous natural law of mass action.

Venus: density of upper atmosphere from measurements of drag on pioneer orbiter.

Measurements of the changes in orbital period of the Pioneer Venus orbiter have yielded estimates of the density of the upper atmosphere of Venus at altitudes in the range from 150 to 200 kilometers. At the lower limit of this range, the density on the dayside of the terminator exhibits a temporal variation of amplitude near 4 x 10(-14) gram per cubic centimeter aboult a mean of approximately 1.4 x 10(-13) gram per cubic centimeter.

[Current aspects on evaluation of assays of factor-VIII activity, factor-VIII associated protein and factor-VIII neutralizing antibody (author's transl)].

In evaluating factor-VIII activity it should be noted that regarding the remaining activity of deficient plasma a linear reference curve is achieved. In the standard population factor-VIII activity and factor-VIII associated protein are distributed approximately lognormally. Due to this distribution certain results have been gained for the optimal choice of localisation and dispersion measures.

Bilateral carotid aneurysms secondary to radiation therapy.

A patient was seen with symptomatic, rapidly expanding aneurysms that developed in both carotid arteries 4 years after bilateral radiation to the neck, left combined mandibular resection, and radical neck dissection. The presenting symptoms were pain and transient ischemic attacks of cerebrovascular insufficiency. The aneurysms were treated uneventfully be resection and vein-graft replacement at 15-day intervals.