Combined simultaneous transcranial and transsphenoidal resection of large-to-giant pituitary adenomas.

Background: While large-to-giant pituitary adenomas (PAs) may be safely removed by experienced surgeons through a single route, the procedure is technically challenging. We present the outcome of a simultaneous combined transcranial and transsphenoidal approach and discuss its applications.

Methods: A retrospective review was conducted on 12 consecutive patients.