[Legal aspects of acute alcoholic intoxication (author's transl)].

This paper deals with the legal aspects of acute alcoholic intoxication. Everybody is obliged in case of helplessness to organise help. Every doctor confronted with an acute alcoholic should careful examine the situation not to overlook other concomitant acute diseases.

[The responsibility of the surgeon (author's transl)].

Juridical survey upon the special problems of surgical carefulness. Emphasis is laid on the necessity of scientific and practical medical cooperation, respect for the patients life and the professional discretion.

[Comparison of the results of radio gold therapy, cobalt 60 teletherapy and chemotherapy in 330 ovarian neoplasms].

From 1960 to 1972, 276 out of 330 cases of ovarian cancer were treated by different techniques of postoperative radiation therapy; 54 advanced cases underwent prospective chemotherapy. Radiogold intraabdominally administered (190 to 300 mCi), telecobalt (5000 rd) or the combination of radiogold and telecobalt was chosen for postoperative radiation therapy. Cyclophosphamide (Endoxan), prednisolone, and gestagenes (Prothil) were given as a long-term chemotherapy.

Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.

Certain substances which influenced nucleic acid metabolism were found to have about the same cytostatic activity on human cells when measured in tissue culture experiments (cell numbers) or in short-term cultures (3-H-uridine incorporation in cell suspensions). By treatment with a dose of cytostatics corresponding to 10 times therapeutic dose, chemosensitive tumors can be distinguished from non-responsive tumors. By using this in vitro test system to investigate the sensitivities of 100 human tumors, it is shown that 28 of these tumors were responsive to adriamycin, daunomycin and Actinomycin D.