Publications by authors named "Hinako Koizumi"
Article Synopsis
- Cisplatin (CDDP) often causes kidney damage (nephrotoxicity), and diuretics are used to try to prevent this effect, but their effectiveness is unclear.
- This study analyzed data from 396 patients receiving CDDP-based chemotherapy to see if a combination of two diuretics, furosemide and mannitol, was better than using one alone in preventing kidney damage.
- Results showed no significant difference in nephrotoxicity rates between the two groups, and factors like high CDDP dose, hypertension, and lack of magnesium supplementation were more critical risks, emphasizing the need for careful monitoring of these patients.
