Publications by authors named "Hina Hanif"

Article Synopsis
  • Recombinant porcine factor VIII (rpFVIII) is used to treat bleeding in patients with acquired hemophilia A.
  • A significant challenge in its effectiveness is the presence of cross-reacting anti-human FVIII antibodies in patients.
  • In this study, 52% of patients with acquired hemophilia A had these antibodies, which resulted in lower FVIII activity levels after receiving rpFVIII.
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Mimosa pudica (MP) is an ornamental plant due to seismonastic movements that close leaves and fall petioles in response to touch, wind, light, heat, cold, and vibration. The seeds of MP secrete smart, biocompatible, and non-toxic mucilage that has captivated researchers due to its widespread use in various fields such as pharmaceuticals and biotechnology. The mucilage is responsive to pH, salt solutions, and solvents and acts as a binder in tablet formulations for targeted drug delivery.

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Article Synopsis
  • * A case involving an eight-year-old girl showed symptoms like short stature, abnormal teeth, fatigue, polydactyly (extra fingers), genu valgum (knock knees), and mild cardiomegaly (enlarged heart), which pointed to EVC.
  • * Diagnosis of EVC relies on detailed radiological tests, and managing the condition benefits from a collaborative approach involving multiple healthcare specialists.
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Correction for 'Recent trends in ozone sensing technology' by Muhammad Mudassir Iqbal , , 2023, , 2798-2822, https://doi.org/10.1039/D3AY00334E.

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Article Synopsis
  • * It discusses the synthesis methods of various ozone-sensing materials, including metal oxides and carbon nanotubes, and explores advancements in ozone-sensing devices and communication technologies.
  • * The review aims to connect knowledge among materials chemists, engineers, and industry professionals, while considering factors that influence ozone measurement accuracy.
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Introduction: Clinicians often order the international normalized ratio (INR) and activated partial thromboplastin time (APTT) to evaluate for the possibility of inherited bleeding disorders despite sensitivities and specificities of 1%-2%. The most accurate tool to evaluate for bleeding disorders is a validated bleeding assessment tool (BAT). Our aim was to reduce coagulation testing by >50% in a large family practice in Ontario, Canada.

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Background: Coagulation testing provides a prime opportunity to make an impact on the reduction of unnecessary laboratory test ordering, as there are clear indications for testing. Despite the prothrombin time/international normalized ratio and activated partial thromboplastin time being validated for specific clinical indications, they are frequently ordered as screening tests and often ordered together, suggesting a gap in understanding of coagulation.

Methods: Based on a needs assessment, we developed an online educational module on coagulation for trainees, incorporating education on testing cost, specificity, and sensitivity.

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  • The study aimed to assess how accurately MRI detects intra-axial gliomas compared to histopathology, which is considered the standard for diagnosis.
  • Conducted from October 2017 to April 2018, patients aged 30-70 with headaches underwent MRI, and results were analyzed by experienced radiologists.
  • Findings showed MRI detected gliomas in 79.90% of patients, while histopathology confirmed them in 85.10%, indicating MRI has high sensitivity (89.31%) and moderate specificity (73.91%).*
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Objective The objective of the present study is to describe high-resolution CT (HRCT) chest manifestations of coronavirus disease 2019 (COVID-19) patients presenting to a tertiary healthcare facility in Punjab, Pakistan, and to analyze the distribution of the disease in lung fields. Additionally, we assess the role of chest CT severity scoring (CT-SS) in determining the severity of pneumonia. Methods In this cross-sectional descriptive study conducted from March 30, 2020, to May 30, 2020, 87 confirmed COVID-19 patients undergoing HRCT scan in a tertiary care facility in Punjab, Pakistan were included.

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Article Synopsis
  • * Conducted at Dow University, the research involved patients aged 30 to 80 suspected of having obstructive jaundice, with results showing that choledocholithiasis was the most common cause of obstruction.
  • * Ultrasound demonstrated a sensitivity of 84.57%, specificity of 79.10%, and an overall diagnostic accuracy of 83.06%, indicating it is quite effective for diagnosing this condition.
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We present a case of hereditary thrombotic thrombocytopenic purpura (hTTP) caused by a previously undescribed mutation in a 36-year-old woman who presented with seizures in the context of a possible infection. Her hematologic manifestations were mild, despite undetectable ADAMTS13 (A Distintegrin and Metalloproteinase with Thrombospondin Motifs 13) activity. Genetic analysis showed a homozygous variant in ADAMTS13 gene which was not previously reported but predicted to be associated with disease.

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Infections due to Dengue virus are widespread throughout the world. Disease starts with mild flu like sickness to a severe intricate condition which results in the death of the patient. Dengue illness has high morbidity and mortality in Pakistan as well as in other Asian countries.

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